ArticleFrontiers in public health2025
Association between atherogenic index of plasma and physical dysfunction: a cross-sectional study of middle-aged and older adults in China.
Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association between atherogenic index of plasma and various metabolic conditions: an umbrella review on meta-analyses.BMC cardiovascular disorders · 2025Pooled it
- Development and Validation of the Composite Renal-Inflammatory-Nutritional-Metabolic Index for Predicting 28-Day Mortality in Critically Ill Patients.Diagnostics (Basel, Switzerland) · 2026Article
- Article
- Association between atherogenic index of plasma and hypertension: exploring the mediating role of body mass index in a Chinese population aged ≥ 45 years.Frontiers in public health · 2025Article
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Authors and funding
7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Background: Physical dysfunction is common in older adults and increases disease risk. The atherogenic index of plasma (AIP) is a promising biomarker for this condition. This study explored the dose-response relationship between AIP and physical dysfunction. Methods: Data from 11,369 CHARLS participants (aged ≥45 years) in 2015 and 2018 were analyzed using univariate and multivariate logistic regression, adjusting for demographics and lifestyle factors. The restricted cubic splines were used to examine possible non-linear associations and visualize the dose-response relationship between AIP and physical dysfunction. ROC curve analysis assessed AIP's predictive performance, and subgroup analyses evaluated interactions. Results: Each interquartile range (IQR) increase in AIP was associated with a 13.4% higher odds of physical dysfunction (adjusted OR = 1.134, 95% CI: 1.066-1.207, Conclusion: Elevated AIP is significantly associated with increased physical dysfunction risk, highlighting its potential as a simple, predictive biomarker.
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