ArticleFrontiers in cardiovascular medicine2025
The relationship between dietary flavonoid intake and hypertension: a cross-sectional study from NHANES.
Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Flavonoids as Immunoregulators: Molecular Mechanisms in Regulating Immune Cells and Their Therapeutic Applications in Inflammatory Diseases.Frontiers in immunology · 2025Review
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6 authors.
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Abstract
Objective: To evaluate the association between dietary flavonoid intake and hypertension using nationally representative data, considering increasing global hypertension prevalence and inconsistent evidence on flavonoids' protective effects. Methods: This cross-sectional study analyzed 8,054 adults aged ≥20 years from NHANES 2007-2010 and 2017-2018. Flavonoid intake was assessed through two 24-hour dietary recalls and categorized into quartiles. Hypertension was defined by blood pressure ≥130/80 mmHg or self-reported diagnosis/medication use. Logistic regression models with progressive adjustment, restricted cubic spline regression for dose-response relationships, and subgroup analyses were conducted, accounting for complex sampling design. Results: After full adjustment, participants in the highest quartile of total flavonoid intake showed 25% lower odds of hypertension compared to the lowest quartile (OR = 0.75, 95% CI: 0.60-0.93, Conclusion: Moderate dietary flavonoid intake, particularly anthocyanidins and flavan-3-ols, is inversely associated with hypertension risk. These associations vary significantly by age and metabolic status, suggesting potential for individualized dietary recommendations for hypertension prevention.
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