Evidence map›Paper›PMID 40521191›Full record

ArticleTheranostics2025

KLK8/HGF/Met signaling pathway mediates diabetes-associated hippocampal neuroinflammation in male mice.

Dan-Hong Xu, Xiao-Yong Zhang, Shi-Yu Liu, Juan Wei, Jun-Hui Zhan, Jian-Kui Du, Yu-Jian Liu, Xiao-Yan Zhu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dan-Hong XuDepartment of Physiology, Naval Medical University, Shanghai, 200433, China.
Xiao-Yong ZhangDepartment of Physiology, Naval Medical University, Shanghai, 200433, China.
Shi-Yu LiuSchool of Kinesiology, The Key Laboratory of Exercise and Health Sciences of Ministry of Education, Shanghai University of Sport, Shanghai, 200438, China.
Juan WeiSchool of Sports and Health, Nanjing Sport Institute, Nanjing, 210014, China.
Jun-Hui ZhanSchool of Kinesiology, The Key Laboratory of Exercise and Health Sciences of Ministry of Education, Shanghai University of Sport, Shanghai, 200438, China.
Jian-Kui DuDepartment of Physiology, Naval Medical University, Shanghai, 200433, China.
Yu-Jian LiuSchool of Kinesiology, The Key Laboratory of Exercise and Health Sciences of Ministry of Education, Shanghai University of Sport, Shanghai, 200438, China.
Xiao-Yan ZhuDepartment of Physiology, Naval Medical University, Shanghai, 200433, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Diabetes Mellitus, ExperimentalHepatocyte Growth FactorHippocampusKallikreinsNeuroinflammatory DiseasesProto-Oncogene Proteins c-metAnimalsDepressionHumansMaleMiceMice, Inbred C57BLMice, KnockoutMicrogliaSignal TransductionHepatocyte Growth FactorHGF protein, mouseKallikreinsProto-Oncogene Proteins c-metPrss18 protein, mouseaerobic exercisedepressiondiabeteshepatocyte growth factormicroglia activationneuroinflammationtissue kallikrein-related peptidase 8

Identifiers

PMID40521191
PMCPMC12159841

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.