Evidence map›Paper›PMID 40521201›Full record

ArticleTheranostics2025

Regulation of heart regeneration by LSD1 through suppressing CEND1.

Huahua Liu, Jinling Dong, Shuang Liu, Yuru Luo, Yuan Fang, Hongyu Su, Weihao Xue, Rui Zhou, Wenjun Huang, Baochang Lai and 11 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Targeting Arterial Dysfunction in Cardiovascular Disease Using Stem Cell-Based Therapies.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Huahua LiuDepartment of Cardiology, First Affiliated Hospital; Cardiometabolic Innovation Center of Ministry of Education, Xi'an Jiaotong University, Xi'an, China.
Jinling DongThe Institute of Cardiovascular Sciences, School of Basic Medical Sciences; Key Laboratory of Environment and Genes Related to Diseases of Ministry of Education, Xi'an Jiaotong University, Xi'an, China.
Shuang LiuCollege of Animal Sciences, Zhejiang University, Hangzhou, Zhejiang, China.
Yuru LuoThe Institute of Cardiovascular Sciences, School of Basic Medical Sciences; Key Laboratory of Environment and Genes Related to Diseases of Ministry of Education, Xi'an Jiaotong University, Xi'an, China.
Yuan FangThe Institute of Cardiovascular Sciences, School of Basic Medical Sciences; Key Laboratory of Environment and Genes Related to Diseases of Ministry of Education, Xi'an Jiaotong University, Xi'an, China.
Hongyu SuThe Institute of Cardiovascular Sciences, School of Basic Medical Sciences; Key Laboratory of Environment and Genes Related to Diseases of Ministry of Education, Xi'an Jiaotong University, Xi'an, China.
Weihao XueDepartment of Cardiology, The Second Affiliated Hospital, Wenzhou Medical University, Wenzhou, China.
Rui ZhouKey Laboratory of Precision Medicine to Pediatric Diseases of Shaanxi Province, Shaanxi Institute for Pediatric Diseases, Xi'an Children's Hospital, Affiliated Children's Hospital, Xi'an Jiaotong University, Xi'an, China.
Wenjun HuangKey Laboratory of Precision Medicine to Pediatric Diseases of Shaanxi Province, Shaanxi Institute for Pediatric Diseases, Xi'an Children's Hospital, Affiliated Children's Hospital, Xi'an Jiaotong University, Xi'an, China.
Baochang LaiThe Institute of Cardiovascular Sciences, School of Basic Medical Sciences; Key Laboratory of Environment and Genes Related to Diseases of Ministry of Education, Xi'an Jiaotong University, Xi'an, China.
Ying XiongDepartment of Cardiology, First Affiliated Hospital; Cardiometabolic Innovation Center of Ministry of Education, Xi'an Jiaotong University, Xi'an, China.
Shuangshuang WangDepartment of Cardiology, the First People's Hospital of Wenling, the Affiliated Hospital of Wenzhou Medical University, Wenling, Zhejiang, China.
Lingli LiangDepartment of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, China.
Zhen WangCollege of Animal Sciences, Zhejiang University, Hangzhou, Zhejiang, China.
Donghong ZhangDepartment of Cardiology, The Second Affiliated Hospital, Wenzhou Medical University, Wenzhou, China.
Lianpin WuDepartment of Cardiology, The Second Affiliated Hospital, Wenzhou Medical University, Wenzhou, China.
Yanmin ZhangKey Laboratory of Precision Medicine to Pediatric Diseases of Shaanxi Province, Shaanxi Institute for Pediatric Diseases, Xi'an Children's Hospital, Affiliated Children's Hospital, Xi'an Jiaotong University, Xi'an, China.
Bin ZhouDepartment of Pediatrics, The University of Chicago, Chicago, IL, USA.
John Y-J ShyyDivision of Cardiology, Department of Medicine, University of California, San Diego, La Jolla, CA, USA.
Zuyi YuanDepartment of Cardiology, First Affiliated Hospital; Cardiometabolic Innovation Center of Ministry of Education, Xi'an Jiaotong University, Xi'an, China.
Yidong WangDepartment of Cardiology, First Affiliated Hospital; Cardiometabolic Innovation Center of Ministry of Education, Xi'an Jiaotong University, Xi'an, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HeartHistone DemethylasesRegenerationAnimalsAnimals, NewbornCell ProliferationDisease Models, AnimalMaleMiceMice, Inbred C57BLMice, KnockoutMyocytes, CardiacHistone DemethylasesKDM1a protein, mouseCend1heart regenerationLSD1

Identifiers

PMID40521201
PMCPMC12159839

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.