Evidence map›Paper›PMID 40521334›Full record

ArticleBMJ public health2025

Prevalence and determinants of complications of type 2 diabetes in a community screening program in Kerala.

Aswathy Sreedevi, Gopal S Pillai, Syama Sathish, Mathews Numpeli, Vishnu B Menon, Steffi A Varughese, Sneha Georgy, Shana Shirin Najeeb, Sumithra Selvam, Jaideep C Menon and 6 more

Abstract read
In one paragraph

Article in BMJ public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Aswathy SreedeviDepartment of Community Medicine, Amrita Institute of Medical Sciences, Kochi, Kerala, India.ORCID 0000-0002-6037-9265
Gopal S PillaiDepartment of Ophthalmology, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.
Syama SathishDepartment of Community Medicine, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.
Mathews NumpeliNational Health Mission, Ernakulam, Kerala, India.
Vishnu B MenonDepartment of Community Medicine, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.ORCID 0000-0002-5770-1612
Steffi A VarugheseDepartment of Community Medicine, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.
Sneha GeorgyDepartment of Community Medicine, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.ORCID 0000-0002-7594-5151
Shana Shirin NajeebDepartment of Community Medicine, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.
Sumithra SelvamDepartment of Biostatistics, St John's National Academy of Health Sciences, Bangalore, Karnataka, India.
Jaideep C MenonDepartment of Cardiology, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.ORCID 0000-0002-0786-8123
Aparna AjayDepartment of Community Medicine, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.
Neeraj V MohandasDepartment of Community Medicine, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.
Rajeesh R NairDepartment of Community Medicine, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.
Vineetha RijjuDepartment of Community Medicine, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.
Revathy Krishnan RadhakrishnanDepartment of Community Medicine, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.ORCID 0009-0003-3376-0030
Prem NairAmrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: This study aims to estimate the prevalence and identify the determinants of peripheral neuropathy (PN), retinopathy and peripheral arterial disease (PAD) among persons with type two diabetes mellitus. Methods: A cross-sectional study with a two-stage cluster sampling was conducted in Kerala in 33 clusters among individuals with type 2 diabetes. The first 85-90 participants who visited the camp with a duration of diabetes of more than a year were enrolled in the study from 33 camps. Thus, a total of 3083 persons with diabetes were enrolled. Mixed effects logistic regression was used to find the factors associated with diabetic retinopathy (DR), PN and PAD. Results: The prevalence of PN, DR and PAD was found to be 48.5% (95% CI 46.74 to 50.26), 28.9% (95% CI 27.36 to 30.56) and 46.3% (95% CI 42.65 to 49.95) respectively. Increased risk of PN was observed among participants with age >60 years (aOR 1.71; 95% CI 1.41 to 2.03), diabetes duration >15 years (aOR 1.88; 95% CI 1.04 to 3.38), unsatisfactory glycosylated haemoglobin (HbA1c) (aOR 1.29, 95% CI 1.05 to 1.61) and unemployment (aOR 1.3, 95% CI 1.09 to 1.59). Women appeared to have a lower risk of 0.68 (95% CI 0.50 to 0.92) compared with men. PAD was higher among those from urban areas (aOR 1.56, 95% CI 1.08 to 2.27). The independent determinants of retinopathy were increasing duration of diabetes from 1.4 (95% CI 1.01 to 1.97) at 6-10 years to 3.58 (95% CI 2.48 to 5.15) more than 15 years and an unsatisfactory HbA1c had a two times (95% CI 1.50, 2.67) higher risk of retinopathy. Conclusion: There is a high prevalence of peripheral vascular disease, PN and retinopathy in Kerala. Retinopathy is more likely with longer duration of type two diabetes and high HbA1c levels. Older age and longer diabetes duration increase the risk of neuropathy, while PAD is more common in urban areas. This highlights the need to include regular screening through the public health system.

Indexed as

Community HealthEpidemiologyMass ScreeningSecondary Prevention

Identifiers

PMID40521334
PMCPMC12164304

What Socratic holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.