Evidence map›Paper›PMID 40522427›Full record

ArticleJournal of epidemiology and global health2025

Prevalence of Alzheimer's Disease and Cardiometabolic Multimorbidity in Older Adults Aged 60 and above in a Large-Scale Representative Sample in Türkiye: A Nationwide Population-Based Cross-Sectional Study.

Mehmet Emin Arayici, Ali Kose

Abstract read
In one paragraph

Article in Journal of epidemiology and global health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
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  4. Prevalence of self-reported hearing loss and its association with depression in individuals aged 15 years and above in a large-scale representative sample: evidence from a nationwide population-based cross-sectional study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mehmet Emin ArayiciDepartment of Public Health, Faculty of Medicine, Dokuz Eylül University, 15 July Medicine and Art Campus, Inciralti-Balcova 35340, Izmir, Turkey. mehmet.e.arayici@gmail.com.ORCID http://orcid.org/0000-0002-0492-5129
Ali KoseDepartment of Public Health, Institute of Health Sciences, Dokuz Eylül University, Izmir, Turkey.ORCID http://orcid.org/0000-0002-8583-8982

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt is a well-established fact that Alzheimer's Disease (AD) is a growing public health challenge worldwide, with increasing prevalence among older adults. Cardiometabolic multimorbidity (CMM) and various sociodemographic and lifestyle factors are acknowledged to influence AD risk. This study aimed to estimate the prevalence of AD and investigate its association with CMM and related sociodemographic and behavioral factors in older adults aged 60 years and above in Türkiye.

methodThis study was conducted using secondary data obtained from the Türkiye Health Survey, provided by the Turkish Statistical Institute (TÜİK). Data were derived from 4630 individuals (weighted sample of 11,331,239) aged 60 years and older. AD prevalence, CMM (hypertension, coronary heart disease, stroke, diabetes, hyperlipidemia), and relevant covariates were evaluated. Multivariable binary logistic regression models were used to identify independent predictors of AD.

resultsThe overall prevalence of AD was 3.8% (95% CI: 3.6-4.9%), slightly higher in females (4.1%, 95% CI: 3.8-5.7%) than males (3.5%, 95% CI: 2.8-4.7%). AD was more common among individuals who were single/divorced (6.4%), had lower education (4.1%), presented with CMM (5.9%), or led sedentary lifestyles (4.9%). In the model adjusted for age, sex, educational status, and marital status, the presence of CMM was significantly associated with increased odds of AD (aOR = 2.081; 95% CI: 1.522-2.844). In the further adjusted model for BMI, tobacco use, alcohol use, and activity during the day, CMM remained a significant predictor of AD (aOR = 1.975, 95% CI: 1.446-2.698).

conclusionsThis large-scale study highlights a substantial burden of AD among older adults in Türkiye, strongly linked to CMM and modifiable social and behavioral factors. The findings of this study highlight the importance of integrated prevention strategies targeting vascular health, education, social support, and physical activity to reduce AD risk.

Indexed as

Alzheimer DiseaseCardiovascular DiseasesMultimorbidityAgedAged, 80 and overCross-Sectional StudiesFemaleHealth SurveysHumansMaleMiddle AgedPrevalenceRisk FactorsTurkeyAlzheimer’s diseaseCardiometabolic multimorbidityOlder adultsPopulation-basedRisk factors

Identifiers

PMID40522427
PMCPMC12170490

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.