SynthesisLangenbeck's archives of surgery2025
Efficacy and safety of therapeutic means for postoperative ileus: an umbrella review of meta-analyses.
Synthesis in Langenbeck's archives of surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The effect of immunonutrition on postoperative ileus following colorectal cancer surgery: a systematic review and meta-analysis of randomized controlled trials.Frontiers in nutrition · 2026Pooled it
- Use of Prucalopride in Severe Ileus in a Critically Ill Patient With Acute Alcoholic Hepatitis and Hepatic Encephalopathy.ACG case reports journal · 2026Article
- Development and comparison of machine learning models for predicting postoperative ileus after posterior thoracolumbar fracture surgery.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
BACKGROUND &
aimsPostoperative ileus is treated using a large number of methods with variable efficacy. This study further clarifies the advantages and disadvantages of existing treatments through umbrella evaluation.
methodThis study conducted a systematic search of databases to select and include meta-analyses discussing the treatment of postoperative ileus. We recalculated the estimated values, 95% confidence intervals, heterogeneity estimates, small study effects, excessive significance tests, and publication biases for each included study using both random and fixed effect models.
resultsA total of 24 meta-analyses, including 27 treatment protocols, were reviewed in this study. Among them, chewing gum, coffee, ERAS(Enhanced Recovery After Surgery) protocols, acupuncture, opioid receptor antagonists, Da-Cheng-Qi-Tang, early enteral nutrition, and Zusanli point injection therapy have been shown to significantly improve postoperative ileus (Class II). Opioid receptor antagonists, early enteral nutrition, ERAS, and chewing gum have also been found to significantly reduce the postoperative hospital stay (Class II).
conclusionEight treatment options can effectively reduce postoperative ileus, while the effectiveness and safety of other treatment options for postoperative ileus require further confirmation through high-quality research.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.