ReviewMicrobial cell factories2025
Microbial synthesis and extraction of value-added metabolites by Rhodotorula toruloides from waste stream: a sustainable approach.
Review in Microbial cell factories, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Selective utilization of formic acid and acetic acid in succinic acid fermentation broth to produce single-cell protein using Rhodotorula glutinis.Bioprocess and biosystems engineering · 2026Article
- Fed-batch lipid production by Rhodosporidium toruloides-7191 using wood hydrolysate.Bioprocess and biosystems engineering · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Rhodotorula toruloides (R. toruloides) has shown great potential for the microbiological synthesis of useful substances, including lipids and carotenoids. Through interconnected metabolic pathways, this oleaginous yeast can synthesize various carotenoids and accumulate significant amounts of lipids. The mevalonate pathway plays a crucial role in the production of these substances. R. toruloides can utilize diverse carbon sources, including waste-derived and sustainable substrates. The product yields are significantly influenced by the optimization of stress factors and culture conditions. Lipid and carotenoid extraction methods have advanced from traditional approaches to more sophisticated techniques, such as enzyme-assisted extraction, ultrasound-assisted extraction, and supercritical fluid extraction. These modern techniques aim to minimize environmental impact while maximizing efficiency and selectivity. Genetic engineering has played a pivotal role in enhancing lipid and carotenoid accumulation in R. toruloides. These strategies involve overexpressing key biosynthetic genes, modifying regulatory elements, and introducing heterologous pathways. Such approaches have expanded the range of chemical synthesis and led to significant improvements in product yields. This study provides a comprehensive insight into the metabolic linkages between lipid and carotenoid biosynthesis, highlighting how stress factors, genetic engineering, and waste-derived substrates influence productivity. Furthermore, present review uniquely explores the role of R. toruloides in environmental bioremediation and wastewater treatment, emphasizing its potential for sustainable waste valorization. Due to its ability to synthesize valuable chemicals from a wide array of carbon sources, R. toruloides is a promising candidate for commercial applications in the feed, food, cosmetic, and biofuel industries.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.