ArticleFrontiers in nutrition2025
Hypoglycemic effect of peony flowers polyphenols based on gut microbiota and metabolomics.
Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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12 authors.
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Abstract
Introduction: Type 2 diabetes mellitus (T2DM), remains a significant global public health concern. Peony has a long history of consumption and medicinal in China, and is rich in polyphenols, flavonoids, polysaccharides, and other components. However, the hypoglycemic activity and underlying mechanism of action of peony flowers polyphenols (PP) remain nebulous. Therefore, we investigate the hypoglycemic effect and mechanism of action of PP on T2DM mice. Methods: PP was extracted and isolated from peony flowers ( Results: The TPC in PP was 81.13 ± 2.89%. The results showed that after 8 weeks of intragastric administration, PP significantly reduced the fasting blood glucose (FBG) ( Conclusions: Consequently, PP may play a hypoglycemic role by regulating intestinal flora and amino acid metabolism pathway. The research establishes a foundation for using PP as a functional food to prevent or alleviate type 2 diabetes mellitus.
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