Evidence map›Paper›PMID 40525424›Full record

ReviewCurrent stem cell research & therapy2025

Breast Milk Stem Cells in the Treatment of Neonatal Diseases.

Lu He, Zhihong Sun, Congcong Zhao, Huiqing Sun

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current stem cell research & therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lu HeDepartment of Neonatology, Henan Children's Hospital Zhengzhou Children's Hospital, 450000, Henan Province, China.
Zhihong SunDepartment of Neonatology, Henan Children's Hospital Zhengzhou Children's Hospital, 450000, Henan Province, China.
Congcong ZhaoDepartment of Neonatology, Henan Children's Hospital Zhengzhou Children's Hospital, 450000, Henan Province, China.
Huiqing SunDepartment of Neonatology, Henan Children's Hospital Zhengzhou Children's Hospital, 450000, Henan Province, China.

Funding

Department of Health Commission of Henan Province 2018010042
6 · The paper itself

Abstract

Breast milk plays an important role in preventing and remission various acute and chronic neonatal diseases. However, the mechanisms through which breast milk performs these effects are still unclear. Recently, research has shown that breast milk contains previously undiscovered cells, called breast milk stem cells (BMSCs), which have the potential for multiple differentiation. These cells have been shown to be expressed in multiple organs and systems of infants after ingestion. This study found that newborns who received BMSCs required a shorter treatment duration and had a better prognosis than those who did not receive BMSCs. This suggests that BMSCs may be able to treat a variety of neonatal diseases, and breast milk may play a role in preventing and mitigating neonatal diseases through BMSCs. In this paper, we summarized the research progress on BMSCs and their therapeutic effects on organs, the possible ways in which BMSCs enter different organs and tissues of the human body, and detailed the types of diseases, modes of action, and mechanisms that BMSCs may play a role in. We aim to pave the way for further clinical and preclinical research on BMSCs, as well as the treatment of neonatal diseases with BMSCs, to provide possible new therapeutic means for treating neonatal diseases and a variety of other diseases.

Indexed as

Infant, Newborn, DiseasesMilk, HumanStem CellsStem Cell TransplantationAnimalsCell DifferentiationFemaleHumansInfant, Newbornbreast milk stem cellsexosomeshypoxic-ischemic encephalopathy.mesenchymal stem cellsnecrotizing enterocolitisNewbornpreterm infants

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.