Evidence map›Paper›PMID 40525910›Full record

ReviewThe oncologist2025

COVID-19 burden of illness in people who are immunocompromised due to cancer: an expert opinion review.

Igor Aurer, Paul Moss, Michel Goldman, Mark Tuthill, Hermann Einsele, Carolina Casañas I Comabella, Samantha James, Katarzyna Borkowska, Fungwe Jah, Sabada Dube and 7 more

Abstract readReview
In one paragraph

Review in The oncologist, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Understanding the Psychological Impacts of Shielding From COVID-19 for Immunocompromised Individuals.Health expectations : an international journal of public participation in health care and health policy · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Igor AurerUniversity Hospital Centre Zagreb, 10000 Zagreb, Croatia.ORCID 0000-0001-6175-4277
Paul MossCollege of Medicine and Health, University of Birmingham, Birmingham, B15 2TT, UK.
Michel GoldmanI3h Institute, Université Libre de Bruxelles, Bruxelles 1050, Belgium.
Mark TuthillUniversity of Oxford, Manor Hospital/Genesis Care, Oxford, OX4 6LB, UK.
Hermann EinseleDepartment of Internal Medicine II, Würzburg University Hospital, Würzburg 97080, Germany.
Carolina Casañas I ComabellaEVIDERA, Evidence, Value and Access by PPD, Granta Park Great Abington, Cambridge, CB21 6GQ, UK.
Samantha JamesEVIDERA, Evidence, Value and Access by PPD, Paris, 94853, France.
Katarzyna BorkowskaEVIDERA, Evidence, Value and Access by PPD, Warsaw, 02-672, Poland.
Fungwe JahMedical Affairs, BioPharmaceuticals Medical, AstraZeneca, Hamburg, 22763, Germany.
Sabada DubeVaccines and Immune Therapies Unit, AstraZeneca, Cambridge, CB2 0AA, UK.
Sarah KleinMedical Affairs, BioPharmaceuticals Medical, AstraZeneca, Groot-Bijgaarden, 1702, Belgium.
Walid KandeilVaccines and Immune Therapies, BioPharmaceuticals Medical, AstraZeneca, Baar, 6340, Switzerland.
Renata YokotaP95 Epidemiology & Pharmacovigilance, Leuven, 3000, Belgium.
Antonio PagliucaStem Cell Transplantation, King's College London/King's College Hospital, London, SE5 9RS, UK.
Gkikas MagiorkinisDepartment of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian, University of Athens, Athens 115 72, Greece.ORCID 0000-0002-0141-4753
Sofie ArnetorpHealth Economics & Payer Evidence, Vaccines & Immune Therapies, BioPharmaceuticals Medical, AstraZeneca, Gothenburg, 431 50, Sweden.
Lennard LeeCentre for Immuno-oncology, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7DQ, UK.

Funding

AstraZeneca
6 · The paper itself

Abstract

From the beginning of the pandemic, people with cancer have experienced a high burden from COVID-19 compared with the general population, both in terms of severe COVID-19-related outcomes and reduced health-related quality of life and mental health. This review presents and discusses expert views on the burden of COVID-19 in individuals with cancer throughout the pandemic. The literature suggests that early in the pandemic, people with cancer had a disproportionately high risk of COVID-19-related hospitalization compared with the general population. This trend continued throughout the pandemic, even after the availability of vaccinations (including boosters) and the emergence of less virulent strains. Rates of hospitalization, intensive care unit admission, and mechanical ventilation varied across studies but were all seen to be higher in people with cancer and COVID-19 compared with the general population or those with cancer alone. Moreover, studies indicated worsened quality of life and mental health in these people during the pandemic and lockdown periods compared with prepandemic or postlockdown periods. Although COVID-19 has entered the endemic phase and is no longer a global health emergency, it remains a significant risk for people with cancer. Generally, COVID-19 continues to increase healthcare resource use, impair mental health, and reduce quality of life in this population, highlighting the need for continued real-world studies. Ongoing research is essential to evaluate the impact of COVID-19 on vaccinated people with cancer, particularly those undergoing systemic cancer therapy who may require continued guidance on preventive measures and treatments to mitigate the risk of severe COVID-19.

Indexed as

Cost of IllnessCOVID-19Immunocompromised HostNeoplasmsHospitalizationHumansMental HealthPandemicsQuality of LifeSARS-CoV-2cost of illnessCOVID-19hospitalizationneoplasmspandemicvaccination

Identifiers

PMID40525910
PMCPMC12200237

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.