Evidence map›Paper›PMID 40526416›Full record

ArticleMicrobial genomics2025

Bacteriophages in

Irene Ortega-Sanz, Alejandro Rubio, Antonio J Pérez-Pulido

Abstract read
In one paragraph

Article in Microbial genomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Irene Ortega-SanzDepartment of Food Technology, Safety and Health, Faculty of Bioscience Engineering, Ghent University, 9000 Gent, Belgium.
Alejandro RubioAndalusian Centre for Developmental Biology (CABD, UPO-CSIC-JA). Faculty of Experimental Sciences (Genetics Area), University Pablo de Olavide, 41013, Seville, Spain.
Antonio J Pérez-PulidoAndalusian Centre for Developmental Biology (CABD, UPO-CSIC-JA). Faculty of Experimental Sciences (Genetics Area), University Pablo de Olavide, 41013, Seville, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) proteins systems provide bacteria with an adaptive immune system against exogenous sequences, such as plasmids and bacteriophages (viruses of prokaryotes). To avoid autoimmunity, the recognition of a very short sequence called the protospacer adjacent motif (PAM) is essential for efficient immune response triggering. This raises the question of whether viruses targeted by certain CRISPR-Cas systems have a higher or lower frequency of their PAM sequences than non-targeted viruses. This was tested here in the opportunistic human pathogen

Indexed as

BacteriophagesClustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas SystemsPseudomonas aeruginosaBase CompositionGenome, ViralHumansprotospacer adjacent motifprotospacersspacersvirus escape

Identifiers

PMID40526416
PMCPMC12174588

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.