Evidence map›Paper›PMID 40527015›Full record

ArticleDrug and alcohol dependence2025

Impact of having a regular drug dealer on obtaining drug checking results consistent with expectations during a drug toxicity crisis in a Canadian setting.

Hannah Esopenko, Brandon D L Marshall, Mark Lysyshyn, Cameron Grant, Susan G Sherman, Evan Wood, Thomas Kerr, Lianping Ti

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Interpol review of forensic drug chemistry, 2022-2025.Forensic science international. Synergy · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hannah EsopenkoDepartment of Medicine, University of British Columbia, 2775 Laurel Street, Vancouver, BC V6H 0A5, Canada.
Brandon D L MarshallDepartment of Epidemiology, Brown University School of Public Health, 121 South Main St, Box G-S-121-2, Providence, RI 02912, United States.
Mark LysyshynVancouver Coastal Health, 601 West Broadway, Vancouver, BC V5Z 4C2, Canada; School of Population and Public Health, University of British Columbia, 2206 East Mall, Vancouver, BC V6T 1Z3, Canada.
Cameron GrantBritish Columbia Centre on Substance Use, 400-1045 Howe Street, Vancouver, BC V6Z 2A9, Canada.
Susan G ShermanDepartment of Health, Behavior, and Society, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, United States.
Evan WoodVancouver Coastal Health, 601 West Broadway, Vancouver, BC V5Z 4C2, Canada.
Thomas KerrBritish Columbia Centre on Substance Use, 400-1045 Howe Street, Vancouver, BC V6Z 2A9, Canada.
Lianping TiBritish Columbia Centre on Substance Use, 400-1045 Howe Street, Vancouver, BC V6Z 2A9, Canada; Department of Medicine, University of British Columbia, 2775 Laurel Street, Vancouver, BC V6H 0A5, Canada. Electronic address: bccsu-lt@bccsu.ubc.ca.

Funding

Evaluation of Drug Checking as a Novel Intervention to Address the Opioid Overdose Crisis Attributable to Fentanyl and its AnaloguesR01DA052381 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI TI, LIANPING · 2021 to 2023
$1.4M
NIDA NIH HHS R01 DA052381
6 · The paper itself

Abstract

backgroundThe unregulated illicit drug supply is a key factor in Canada's ongoing drug crisis and a significant public health concern. This study explores whether having a regular drug dealer impacts the likelihood of obtaining drug checking results consistent with expectations (i.e., the drug the individual expected was detected using drug checking technology, irrespective of other substances present).

methodsData were derived from a cross-sectional study, conducted between March 2020 and August 2023, across 22 harm reduction sites in British Columbia (BC), Canada. These sites operate drug checking services using Fourier-transform infrared spectroscopy (FTIR) and immuno-assay strips. Logistic regression analysis examined the relationship between having a regular dealer and obtaining drug checking results consistent with expectations.

resultsA total of 322 participants were included in the study: 268 (83.2 %) reported a regular drug dealer and 260 (80.7 %) obtained results consistent with their primary drug expectation. Among those with a regular dealer, 240 (74.8 %) obtained drugs from them 100 % of the time. After adjusting for confounders, multivariable logistic regression analysis found no significant association between having a regular dealer and obtaining expected drug checking results (adjusted odds ratio = 1.10; 95 % confidence interval: 0.48 - 2.52, p-value = 0.827).

conclusionDespite assumptions that a regular dealer increases the likelihood of receiving results consistent with primary drug expectations, this study found no association. These findings support the importance of drug checking, education on the unpredictability of the unregulated drug supply, and other essential harm reduction services in addressing Canada's public health crisis.

Indexed as

Illicit DrugsSubstance Abuse DetectionAdultBritish ColumbiaCanadaCross-Sectional StudiesFemaleHarm ReductionHumansMaleMiddle AgedSubstance-Related DisordersYoung AdultIllicit DrugsDrug checkingDrug dealerDrug toxicityPublic healthUnregulated illicit drug supply

Identifiers

PMID40527015
PMCPMC13170610

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.