Evidence map›Paper›PMID 40527813›Full record

SynthesisMedicine2025

Treatment of chronic urticaria with traditional Chinese medicine: A systematic review, meta-analysis, and medication regularity.

Ruyu Chen, Zuxi Cen, Keyao Zheng, Yu Chen, Tiejun Chen, Chujie Chen

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ruyu ChenGuangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China.ORCID 0009-0005-4627-6867
Zuxi CenGuangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China.
Keyao ZhengDongguan Qishi Town Community Health Service Center, Dongguan, Guangdong Province, China.
Yu ChenDongguan Qishi Town Community Health Service Center, Dongguan, Guangdong Province, China.
Tiejun ChenDongguan Qishi Town Community Health Service Center, Dongguan, Guangdong Province, China.
Chujie ChenGuangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China.

Funding

the Guangdong Provincial Department of Science and Technology Fund Project No. 2020B1111100011
6 · The paper itself

Abstract

backgroundTraditional Chinese medicine (TCM) is often used to treat chronic urticarial (CU), so its efficacy and safety on CU were studied according to systematic review and meta-analysis.

methodsBy searching PubMed, Wanfang, CNKI, and other databases for the literature on the treatment of CU with TCM in the past 10 years (2013-2023), the PICOS principle was used as the criterion for inclusion and exclusion of literature, and the quality of the included literature studies was systematically reviewed according to the Cochrane systematic review method and software RevMan5.3.

resultsA total of 14 articles were included, including 1192 patients. According to the analysis results, the total effective rate of TCM in the treatment of CU was (RR = 1.23, 95% confidence interval (CI) [1.16-1.29], P < .00001), the incidence of adverse reactions and recurrence rates were (RR = 0.23, 95% CI [0.13-0.39], P < .00001) and (RR = 0.24, 95% CI [0.13-0.43], P < .00001), and the symptom score was (MD = -0.38, 95% CI [-0.81-0.05], P = .08). The most frequently used Chinese herbs were Windbreak, Licorice, Angelica sinensis, Schizonepeta, Cicada slough, Cassia twig, Astragalus membranaceus, schisandra chinensis, Cortex dictamni and Dark plum.

conclusionTCM has great advantages in the treatment of CU, can effectively improve the symptoms, the curative effect is stable and safe, but there are still some deficiencies in the standardization of curative effect evaluation.

Indexed as

Chronic UrticariaDrugs, Chinese HerbalMedicine, Chinese TraditionalHumansTreatment OutcomeDrugs, Chinese HerbalChronic urticariameta-analysistherapeutic effecttraditional Chinese medicine

Identifiers

PMID40527813
PMCPMC12173312

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.