Evidence map›Paper›PMID 40527844›Full record

ArticleMedicine2025

The Regentime stem cell procedure efficacy in asthma treatment: A case report.

Rita T Boulos, Cynthia F Najjoum, Vanessa J Mansour, Elsa A El Asmar, Nassim H Abi Chahine

Abstract readCase Reports
In one paragraph

Article in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rita T BoulosRegentime Clinic, Beirut, Lebanon.ORCID 0000-0002-9855-5543
Cynthia F Najjoum
Vanessa J Mansour
Elsa A El Asmar
Nassim H Abi Chahine

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

rationaleAsthma is a chronic respiratory condition affecting millions worldwide. It is characterized by airway inflammation leading to airflow obstruction and bronchial hyperresponsiveness. Despite optimal pharmacological treatment, some people fail to achieve full control of their symptoms and suffer from recurrent debilitating asthma attacks. PATIENT CONCERNS: We report the case of a 54-year-old female patient who originally presented for stem cell treatment of her ankle. She complained of chronic left ankle pain and swelling that worsened with weight-bearing activities. During her medical history taking, she described experiencing dyspnea and wheezing both during the daytime and on more than 1 night weekly. DIAGNOSES: She had an obstructive pattern on spirometry and her symptoms were consistent with the diagnosis of moderate persistent asthma. She was also previously diagnosed with osteoarthritis affecting her tibiotalar and talocalcaneal joints.

interventionsThe patient received partially differentiated autologous stem cells in her affected joints. Another portion of stem cells was treated and administered to her via inhalation according to the Regentime protocol for lung regeneration. OUTCOMES: Upon regular follow-up, the patient reported gradual improvement of her osteoarthritis symptoms, reaching full recovery of the ankle within 5 months following treatment. She also noted the progressive amelioration of her asthma manifestations until their disappearance during the first month after stem cell administration. Her clinical remission was maintained for at least 24 months with ongoing follow-up to date and progressive improvement on physical examination. LESSONS: The successful outcome of this case marks the potential of the Regentime stem cell protocol for lung regeneration as a promising therapeutic approach for managing chronic respiratory conditions such as asthma.

Indexed as

AsthmaStem Cell TransplantationFemaleHumansMiddle AgedOsteoarthritisTreatment Outcomeasthmacase reportlung regenerationstem cell therapythe Regentime procedure

Identifiers

PMID40527844
PMCPMC12173279

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.