Evidence map›Paper›PMID 40528151›Full record

ArticleHealth services research2025

Insulin Out-of-Pocket Spending Caps and Employer-Sponsored Insurance: Changes in Out-of-Pocket and Total Costs for Insulin and Healthcare.

Khrysta A Baig, Carrie E Fry, Melinda B Buntin, Alvin C Powers, Stacie B Dusetzina

Abstract read
In one paragraph

Article in Health services research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Khrysta A BaigDepartment of Health Policy, Vanderbilt University, Nashville, Tennessee, USA.ORCID https://orcid.org/0000-0002-2318-2308
Carrie E FryDepartment of Health Policy, Vanderbilt University, Nashville, Tennessee, USA.ORCID https://orcid.org/0000-0003-0661-847X
Melinda B BuntinDepartment of Health Policy, Vanderbilt University, Nashville, Tennessee, USA.
Alvin C PowersDivision of Diabetes, Endocrinology and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Stacie B DusetzinaDepartment of Health Policy, Vanderbilt University, Nashville, Tennessee, USA.

Funding

Vanderbilt Diabetes Research CenterP30DK020593 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI OWEN P MCGUINNESS · 2012 to 2026
$29.3M
Arnold VenturesCommonwealth FundNIDDK NIH HHS DK020593NIDDK NIH HHS P30 DK020593
6 · The paper itself

Abstract

objectiveTo estimate the impact of state-level insulin out-of-pocket caps on changes in out-of-pocket and total costs of insulin and healthcare for insulin users with employer-sponsored insurance. STUDY SETTING AND

designWe evaluated changes in costs using a quasi-experimental (triple difference-in-differences; "DDD") design to analyze multi-carrier claims from insulin users enrolled in fully insured (state-regulated) and self-funded (generally exempt) employer-sponsored plans in 10 states with caps by January 2021 compared to no-cap states pre-/post-cap implementation. Primary outcomes were changes in insulin out-of-pocket spending, total (plan + member) paid for insulin, and total healthcare costs. Secondary outcomes were intermediary (e.g., pharmaceutical) changes in out-of-pocket and total costs. DATA SOURCES AND ANALYTIC SAMPLE: In the policy year (no-cap states: 2021), we identified 218,441 insulin-users in the Health Care Cost Institute 2.0 Dataset (cap states: 27,834 in fully insured and 22,131 in self-funded plans; no-cap states: 97,239 in fully insured and 71,237 in self-funded plans) and 215,635 in the year prior. PRINCIPAL

findingsWe found evidence of modest decreases in 30-day standardized (DDD: -$5 [95% CI: -$6 to -$4]; p < 0.001) and annual (DDD: -$67 [95% CI: -$82 to -$51]; p < 0.001) insulin out-of-pocket spending. Savings increased by spending quantile (e.g., 95th-percentile change:-$347 [95% CI: -$460 to $233]). Difference-in-differences (DiD) comparing fully insured to self-funded plans within cap-states showed larger changes (e.g., 95th-percentile annual insulin out-of-pocket:-$484 [95% CI: -$651 to -$318]), likely due to policy spillover effects (i.e., fully insured plans decreased out-of-pocket in no-cap states). Change in annual total paid for healthcare was not statistically significant (DDD:-$1082 [95% CI: -$2918 to $755]; p < 0.25). We saw no evidence of caps increasing out-of-pocket or total spending on insulin, prescriptions, or healthcare.

conclusionsOur findings suggest early caps had modest effects on out-of-pocket spending among fully insured insulin users, with larger savings for those at the top of the spending distribution and no total cost increases. Policy effects may be greater than observed; they likely lag implementation and develop over time.

Indexed as

Health Benefit Plans, EmployeeHealth Care CostsHealth ExpendituresHypoglycemic AgentsInsulinAdultFemaleHumansMaleMiddle AgedUnited StatesHypoglycemic AgentsInsulincost‐related nonadherenceemployer‐sponsored health insuranceinsulin cost‐sharing capsinsulin out‐of‐pocket capsvalue‐based insurance design

Identifiers

PMID40528151
PMCPMC12636258

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.