Evidence map›Paper›PMID 40528342›Full record

ArticleBiophysical journal2025

A Bayesian framework for systems model refinement and selection of calcium signaling.

Xuan Fang, Peter Varughese, Sara Osorio-Valencia, Aleksey V Zima, Peter M Kekenes-Huskey

Abstract read
In one paragraph

Article in Biophysical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xuan FangDepartment of Cell and Molecular Physiology, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois. Electronic address: xfang2@luc.edu.
Peter VarugheseDepartment of Cell and Molecular Physiology, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois.
Sara Osorio-ValenciaDivision of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, Chicago, Illinois.
Aleksey V ZimaDepartment of Cell and Molecular Physiology, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois.
Peter M Kekenes-HuskeyDepartment of Cell and Molecular Physiology, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois.

Funding

New mechanisms of SERCA2a regulation: role of luminal calciumR01HL151990 · NHLBI · LOYOLA UNIVERSITY CHICAGO · PI ZIMA, ALEKSEY V · 2021 to 2024
$1.7M
Probing macrophage cell nucleotide sensing and calcium signaling through computationR35GM148284 · NIGMS · LOYOLA UNIVERSITY CHICAGO · PI Peter Michael Kekenes-Huskey · 2023 to 2026
$1.5M
New mechanisms of cardiac ryanodine receptor dysfunction during oxidative stress: the role of intersubunit cross-linkingR01HL176568 · NHLBI · LOYOLA UNIVERSITY CHICAGO · PI Aleksey V Zima · 2025 to 2026
$1.3M
NHLBI NIH HHS R01 HL151990NHLBI NIH HHS R01 HL176568NIGMS NIH HHS R35 GM148284
6 · The paper itself

Abstract

Calcium (Ca

Indexed as

Calcium SignalingModels, BiologicalAdenosine TriphosphateAnimalsBayes TheoremCalciumHEK293 CellsHumansMyoblastsRyanodine Receptor Calcium Release ChannelSarcoplasmic Reticulum Calcium-Transporting ATPasesAdenosine TriphosphateCalciumRyanodine Receptor Calcium Release ChannelSarcoplasmic Reticulum Calcium-Transporting ATPases

Identifiers

PMID40528342
PMCPMC12414710

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.