Evidence map›Paper›PMID 40528481›Full record

ArticleObesity (Silver Spring, Md.)2025

Food insecurity and the risk of diabetes: understanding the role of BMI as a mediator and moderator.

Cindy W Leung, Alessandra Uriarte, Minal R Patel, Markell Miller, Eileen Spring, Julia A Wolfson, Alicia J Cohen, Michele Heisler, Wei Hao

Abstract read
In one paragraph

Article in Obesity (Silver Spring, Md.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Cindy W LeungDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0001-6718-3487
Alessandra UriarteDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Minal R PatelDepartment of Health Behavior and Health Education, University of Michigan School of Public Health, Ann Arbor, Michigan, USA.
Markell MillerFood Gatherers, Ann Arbor, Michigan, USA.
Eileen SpringFood Gatherers, Ann Arbor, Michigan, USA.
Julia A WolfsonDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Alicia J CohenCenter for Innovation in Long Term Services and Supports, Veterans Affairs Providence Healthcare System, Providence, Rhode Island, USA.
Michele HeislerDepartment of Health Behavior and Health Education, University of Michigan School of Public Health, Ann Arbor, Michigan, USA.
Wei HaoDepartment of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA.

Funding

Research BaseP30DK092926 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MARY ELLEN MICHELE HEISLER, ADESUWA B OLOMU · 2011 to 2026
$10.0M
HSRD VA IK2 HX003013NIDDK NIH HHS P30 DK092926NIDDK NIH HHS P30DK092926U.S. Department of Veterans Affairs CDA 20-037
6 · The paper itself

Abstract

objectiveThis retrospective cohort study examined BMI as a mediator and moderator of the association between food insecurity and diabetes.

methodsData came from the electronic health records of 74,174 primary care patients at a large academic medical center. We used multivariate Poisson regression models to examine the association between food insecurity and diabetes. We used causal mediation analysis to evaluate the direct and indirect effects by which BMI mediates and moderates this association and the extent to which these effects varied by age, sex, and race and ethnicity.

resultsDuring the 5-year period, 6.2% of patients were newly diagnosed with diabetes. Food insecurity was associated with a higher risk of diabetes (relative risk [RR] 1.19, 95% CI: 1.03-1.36) after multivariate adjustment. In mediation analysis, BMI was a significant mediator of the association between food insecurity and diabetes (natural indirect effect: RR 1.10, 95% CI: 1.06-1.14). When accounting for an interaction with BMI, BMI remained a significant mediator (natural indirect effect: RR 1.12, 95% CI: 1.0-1.17). In subgroup analyses, the mediator-moderator effect of BMI was stronger among adults <45 years old and female patients; there were no differences by race or ethnicity.

conclusionsOur findings support BMI as a mediator and moderator of the association between food insecurity and diabetes.

Indexed as

Body Mass IndexDiabetes MellitusFood InsecurityFood SupplyAdultAgedFemaleHumansMaleMiddle AgedObesityRetrospective StudiesRisk Factors

Identifiers

PMID40528481
PMCPMC12213221

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.