Evidence map›Paper›PMID 40528713›Full record

ArticleNeurogastroenterology and motility2026

Consensus on the Management of Anesthetic Agents During Digestive Motility Measurements and Proposal of a Standardized Protocol for Anesthesia (French Neuro Gastroenterology Group GFNG and Committee of Anesthetic French Experts).

Domitille Renard, Thomas Clavier, Osama Abou-Arab, Gérard Amarenco, Emmanuel Besnier, Alice Blet, Matthieu Boisson, Charlène Brochard, Benoit Coffin, Audrey De Jong and 20 more

Abstract read
In one paragraph

Article in Neurogastroenterology and motility, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

Domitille RenardDepartment of Anesthesiology, Critical Care and Perioperative Medecine, CHU Rouen, Rouen, France.ORCID https://orcid.org/0009-0002-8259-1504
Thomas ClavierDepartment of Anesthesiology, Critical Care and Perioperative Medecine, CHU Rouen, Rouen, France.
Osama Abou-ArabAnesthesiology, Critical Care Medecine and Perioperative Medecine Department, Amiens University Hospital, Amiens, France.
Gérard AmarencoSorbonne Université, GRC n°1, Groupe de Recherche Clinique en Neuro-Urologie - GREEN, AP-HP, Hôpital de la Pitié-Salpêtrière, Paris, France.
Emmanuel BesnierDepartment of Anesthesiology, Critical Care and Perioperative Medecine, CHU Rouen, Rouen, France.
Alice BletDepartment of Anaesthesiology and Critical Care, IHU EVEREST, Croix Rousse University Hospital, Hospices Civils de Lyon, INSERM U1052, Cancer Research Center of Lyon, University Lyon 1, Lyon, France.
Matthieu BoissonUniversité de Poitiers, INSERM, PHAR2, CHU de Poitiers Service d'Anesthésie Réanimation Médecine Péri-opératoire, Poitiers, France.
Charlène BrochardDiseases of the Digestive Tract Department, Functional Digestive Explorations Division, Pontchaillou University Hospital, Rennes University, Rennes, France.ORCID https://orcid.org/0000-0001-7354-6301
Benoit CoffinUniversité de Paris Cité, Département d'Hépato-Gastro-Entérologie, Hôpital Louis Mourier, DMU ESPRIT AP-HP Nord, Colombes, France.ORCID https://orcid.org/0000-0002-0606-4158
Audrey De JongAnesthesiology, Critical Care Medicine and Perioperative Medicine Department, Montpellier University Hospital, St-Eloi Hospital, INSERM U1046, CNRS UMR, PhyMedExp, University of Montpellier, Montpellier, France.
Denis FrascaCHU de Poitiers, INSERM CIC1402, Université de Poitiers, Poitiers, France.
Marc GarnierAnesthesiology, Critical Care Medicine and Perioperative Medicine Department, AP-HP Tenon Hospital, Paris, France.
Aurelie GouelAnesthesiology, Critical Care Medicine and Perioperative Medicine Department, AP-HP Hospital, Paris, France.
Jérémie JacquesHepatogastroenterology Department, Limoges University Hospital, Limoges, France.
Arthur JamesSorbonne Université, GRC 29, Groupe de Recherche Clinique en Anesthésie Réanimation médecine Périopératoire, ARPE, Paris, France.
Yoann LauneyAnesthesiology, Critical Care Medicine and Perioperative Medicine Department, Rennes University Hospital, Rennes, France.
Anne-Marie LeroiDepartment of Digestive Physiology, ADEN UMR1073, Nutrition, Inflammation and Microbiota-Gut-Brain Axis, CHU Rouen, CIC-CRB 1404, Univ Rouen Normandie, INSERM, Normandie Univ, Rouen, France.
Chloé MelchiorDepartment of Gastroenterology, Univ Rouen Normandie, INSERM, Normandie Univ, ADEN UMR1073, Nutrition, Inflammation and Microbiota-Gut-Brain Axis, CHU Rouen, Rouen, France.
Daphné MicheletAnesthesiology, Critical Care Medicine and Perioperative Medicine Department, Reims University Hospital, C2S Laboratory, Reims Champagne Ardenne University, Reims, France.
François MionDigestive Physiology Department, Hospices Civils de Lyon, INSERM, LabTAU, Lyon University, Lyon, France.ORCID https://orcid.org/0000-0002-2908-1591
Maxime NguyenAnesthesiology, Critical Care Medicine and Perioperative Medicine Department, INSERM U1231, Dijon Hospital University, Dijon, France.
Emmanuel RineauAnesthesiology, Critical Care Medicine and Perioperative Medicine Department, Angers University Hospital, Angers, France, Univ Angers, MITOVASC Inserm U1083 - CNRS 6015, Team CARME, Angers, France.
Amélie RolléAnesthesiology, Critical Care Medicine and Perioperative Medicine Department, Guadeloupe University Hospital, French Caribbean, France.
Sabine RomanDigestive Physiology Department, Hospices Civils de Lyon, INSERM, LabTAU, Lyon University, Lyon, France.ORCID https://orcid.org/0000-0002-7798-7638
Stéphanie SigautAnesthesiology, Critical Care Medicine and Perioperative Medicine Department, AP-HP Beaujon Hospital, Paris, France.
Heithem SolimanUniversité de Paris Cité, Département d'Hépato-Gastro-Entérologie, Hôpital Louis Mourier, DMU ESPRIT AP-HP Nord, Colombes, France.ORCID https://orcid.org/0000-0003-1644-7272
Fabien WuestenberghsDepartment of Gastroenterology and Digestive Oncology, Sorbonne Paris Nord University, Hôpital Avicenne, AP-HP, Bobigny, France.
Frank ZerbibBordeaux University Hospital, Centre Medico-Chirurgical Magellan, Haut-Lévêque Hospital and Gastroenterology Department, Bordeaux University, INSERM CIC, Bordeaux, France.ORCID https://orcid.org/0000-0002-6802-2121
Guillaume GourcerolDepartment of Digestive Physiology, ADEN UMR1073, Nutrition, Inflammation and Microbiota-Gut-Brain Axis, CHU Rouen, CIC-CRB 1404, Univ Rouen Normandie, INSERM, Normandie Univ, Rouen, France.ORCID https://orcid.org/0000-0001-8220-9155
Charlotte DesprezDepartment of Digestive Physiology, ADEN UMR1073, Nutrition, Inflammation and Microbiota-Gut-Brain Axis, CHU Rouen, CIC-CRB 1404, Univ Rouen Normandie, INSERM, Normandie Univ, Rouen, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTechniques for measuring digestive motility are becoming increasingly precise and enable therapeutic interventions. However, while most of these interventions require general anesthesia, there is limited data on the impact of anesthetic agents on these measurements, and no standardized anesthesia protocol currently exists to guide such procedures. Our working group carried out two Delphi processes involving experts in neurogastroenterology and anesthesiology to reach a consensus on which drugs affect these measurements and to establish an anesthesia protocol.

methodTwo expert groups were formed, comprising 13 neurogastroenterology experts from the French Neuro-Gastroenterology Group (GFNG) and 15 full- or associate professors in anesthesia and intensive care. The first Delphi process involved the neurogastroenterologists and aimed to identify which anesthetic drugs influenced digestive pressure measurements. The second Delphi process, involving anesthetists, sought to develop an anesthesia protocol. Each expert indicated their level of agreement with each statement using a 6-point Likert scale. A statement was endorsed when at least 80% of experts agreed with it. The strength of evidence for each statement was evaluated using the GRADE system.

resultsThe Delphi process with neurogastroenterologists was conducted over three rounds and ultimately resulted in 91 amendments. The second Delphi process with anesthetists took place over two rounds and included 28 amendments, leading to the development of an anesthesia protocol.

conclusionTo our knowledge, this work is the first to establish an expert consensus on anesthetic agents that can affect digestive motility measurements and to propose an anesthesia protocol that accounts for the needs of neurogastroenterologists.

Indexed as

AnesthesiaAnestheticsGastrointestinal MotilityConsensusDelphi TechniqueFranceGastroenterologyHumansAnestheticsanesthesia protocolDelphidigestive motilityexperts groupsFLIPmanometry

Identifiers

PMID40528713
PMCPMC13121879

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.