Evidence mapPaperPMID 40528752Full record

Observational studyHypertension (Dallas, Tex. : 1979)2025

Vascular Assessment Stratifying Preeclampsia Risk in Overweight/Obese Women.

Christos Chatzakis, Laura A Magee, Renata Castello, Gerardo Miranda, Peter von Dadelszen, Kypros H Nicolaides, Marietta Charakida

Abstract readObservational Study
In one paragraph

Observational study in Hypertension (Dallas, Tex. : 1979), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Christos ChatzakisFetal Medicine Research Institute, King's College Hospital, London, United Kingdom (C.C., R.C., G.M., K.H.N., M.C.).ORCID 0000-0002-5895-6887
Laura A MageeInstitute of Women and Children's Health, School of Life Course and Population Sciences, King's College London, United Kingdom (L.A.M., P.v.D., K.H.N.).ORCID 0000-0002-1355-610X
Renata CastelloFetal Medicine Research Institute, King's College Hospital, London, United Kingdom (C.C., R.C., G.M., K.H.N., M.C.).ORCID 0000-0002-3705-8615
Gerardo MirandaFetal Medicine Research Institute, King's College Hospital, London, United Kingdom (C.C., R.C., G.M., K.H.N., M.C.).
Peter von DadelszenInstitute of Women and Children's Health, School of Life Course and Population Sciences, King's College London, United Kingdom (L.A.M., P.v.D., K.H.N.).ORCID 0000-0003-4136-3070
Kypros H NicolaidesFetal Medicine Research Institute, King's College Hospital, London, United Kingdom (C.C., R.C., G.M., K.H.N., M.C.).ORCID 0000-0003-1266-0711
Marietta CharakidaFetal Medicine Research Institute, King's College Hospital, London, United Kingdom (C.C., R.C., G.M., K.H.N., M.C.).ORCID 0000-0003-4214-5059

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOverweight and obesity greatly increase the risk of preeclampsia. There is a need to better risk-stratify these women in pregnancy and channel resources to those who can benefit most.

methodsProspective observational study of 11 962 women with singleton pregnancies attending a routine assessment at 35+0 to 36+6 weeks' gestation at King's College Hospital, London, United Kingdom. Women were categorized by their body mass index at 11 to 13 weeks' gestation as normal weight (18.5-24.9 kg/m

resultsIn this cohort, 28.4% were overweight and 17.9% were obese. Preeclampsia developed more often in overweight/obese (versus normal weight) women (6.0% versus 1.7%, respectively;

conclusionsRisk factors for term preeclampsia are largely similar between overweight/obese and normal-weight women, except for Black and South Asian women, who face a particularly high risk within the overweight/obese group. Maternal vascular assessment may serve as a valuable tool for stratifying the risk for term preeclampsia in these populations.

Indexed as

ObesityOverweightPre-EclampsiaUterine ArteryAdultBody Mass IndexFemaleHumansPregnancyProspective StudiesPulse Wave AnalysisRisk AssessmentRisk FactorsVascular Stiffnessbody mass indexobesitypreeclampsiapulse wave analysisuterine artery

Identifiers

PMID40528752
PMCPMC12366733

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.