Evidence mapPaperPMID 40528834Full record

ReviewResearch and reports in urology2025

Patient Reported Outcomes and Treatment-Associated Complications as a Consideration in Selecting Localized Prostate Cancer Management.

Tivoli Nguyen, Christine Lightfoot, David May, Jacob W Greenberg, Louis Spencer Krane

Abstract readReview
In one paragraph

Review in Research and reports in urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tivoli NguyenDepartment of Urology, Tulane University School of Medicine, New Orleans, LA, USA.
Christine Lightfoot *Department of Urology, Tulane University School of Medicine, New Orleans, LA, USA.ORCID 0009-0001-8609-0267
David May *Department of Urology, Tulane University School of Medicine, New Orleans, LA, USA.
Jacob W GreenbergDepartment of Urology, Tulane University School of Medicine, New Orleans, LA, USA.
Louis Spencer KraneSection of Urology, Southeast Louisiana Veterans Healthcare System, New Orleans, LA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Localized prostate cancer (PCa) remains the most common noncutaneous cancer in men, with numerous management options tailored to individual patient needs. This review examines the role of patient-reported outcomes (PROs) in guiding the management of localized PCa, focusing on the impact of various treatments on long-term quality of life. Standard therapies, including radical prostatectomy, radiotherapy, and active surveillance, are discussed alongside emerging focal therapies. Each treatment modality presents distinct risks, notably urinary incontinence, erectile dysfunction, bowel issues, and cancer recurrence. Understanding these adverse effects in terms of PROs is critical for patients and healthcare providers to engage in shared decision-making, enabling personalized treatment plans based on clinical outcomes and patient values. The incorporation of PROs into treatment selection emphasizes the significance of balancing oncologic control with functional outcomes, such as sexual, bowel, and urinary health. The importance of patient counseling is underscored, ensuring patients are fully informed about potential complications and long-term implications. This review advocates for personalized, evidence-based management strategies that align therapeutic decisions with individual patient preferences, optimizing both survival and quality of life. Enhanced communication between patients and clinicians, informed by PROs, is critical for minimizing decisional regret and maximizing satisfaction in the management of localized PCa.

Indexed as

complicationsfocal therapypatient reported outcomesprostate cancerradical prostatectomyradiotherapytreatment

Identifiers

PMID40528834
PMCPMC12170866

What Socratic holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.