Evidence map›Paper›PMID 40529112›Full record

Trial reportDepression and anxiety2025

Impact of a Mindfulness-Based Intervention on Symptoms and Emotion Regulation Strategies in Young Adolescents From the General Population: A Randomized Controlled Trial.

Camille Piguet, Zeynep Celen, Ben Meuleman, Zoé Schilliger, Mariana Magnus Smith, Erik Mendola, Eleonore Pham, Sondes Jouabli, Vladimira Ivanova, Ryan J Murray and 2 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Depression and anxiety, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Camille PiguetGeneral Pediatrics Division, Women, Child and Adolescent Department, Geneva University Hospitals and Faculty of Medicine, University of Geneva, Geneva, Switzerland.ORCID 0000-0003-4317-0918
Zeynep CelenPsychiatric Department, Faculty of Medicine, University of Geneva, Geneva, Switzerland.ORCID 0000-0002-1227-6587
Ben MeulemanPsychiatric Department, Faculty of Medicine, University of Geneva, Geneva, Switzerland.ORCID 0000-0003-2225-8320
Zoé SchilligerCenter for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital and the University of Lausanne, Lausanne, Switzerland.ORCID 0000-0003-2327-869X
Mariana Magnus SmithGeneral Pediatrics Division, Women, Child and Adolescent Department, Geneva University Hospitals and Faculty of Medicine, University of Geneva, Geneva, Switzerland.ORCID 0000-0001-9756-3472
Erik MendolaGeneral Pediatrics Division, Women, Child and Adolescent Department, Geneva University Hospitals and Faculty of Medicine, University of Geneva, Geneva, Switzerland.ORCID 0009-0008-3436-4693
Eleonore PhamPsychiatric Department, Faculty of Medicine, University of Geneva, Geneva, Switzerland.ORCID 0009-0003-3193-0008
Sondes JouabliPsychiatric Department, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Vladimira IvanovaPsychiatric Department, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Ryan J MurrayPsychiatric Department, Faculty of Medicine, University of Geneva, Geneva, Switzerland.ORCID 0000-0002-5322-6527
Paul KlauserCenter for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital and the University of Lausanne, Lausanne, Switzerland.ORCID 0000-0003-0284-4947
Arnaud MerglenGeneral Pediatrics Division, Women, Child and Adolescent Department, Geneva University Hospitals and Faculty of Medicine, University of Geneva, Geneva, Switzerland.ORCID 0000-0001-5654-8428

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adolescence is marked by major puberty-induced changes including increased reactivity to stress and a peak incidence of mental disorders. The implementation of early interventions during this developmental period is essential to prevent mental disorders. In this clinical trial, we examined the effects of a mindfulness-based intervention (MBI) on internalizing symptoms, affects, and emotion-regulation strategies in a nonclinical sample of young adolescents. Seventy adolescents (41 girls) from the general population, aged between 13 and 15 years, were enrolled in a randomized controlled trial (RCT) that compared an 8-week MBI designed for adolescents and a waiting list. Levels of stress, anxiety and depressive symptoms, positive and negative affects, as well as emotion regulation strategies were measured before and after the intervention (4.8 weeks ± 4 SD) using self-reported questionnaires. We found no effect of our MBI on all self-reported measures, including stress, anxiety, depression, and positive and negative affects, as well as an emotion regulation strategies. Trait mindfulness was negatively correlated with measures of stress, anxiety, and negative affects. The intervention was very well accepted (only one dropout) with a high degree of satisfaction among participants. Individual responses to the intervention were very heterogeneous. Mindfulness practice in non-help-seeking adolescents was very well received, but did not show any benefit on symptoms, affects, or emotion regulation. This is consistent with the literature suggesting a better response in clinical than in nonclinical samples. Longer-term effects remain to be investigated, as does the possibility of identifying individuals who respond best to this early intervention.

Indexed as

AnxietyDepressionEmotional RegulationMindfulnessStress, PsychologicalAdolescentFemaleHumansMaleTreatment Outcomeadolescentsemotion regulationinternalized symptomsmindfulnessrandomized controlled trial

Identifiers

PMID40529112
PMCPMC12173555

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.