Evidence map›Paper›PMID 40529404›Full record

ArticleFrontiers in sports and active living2025

Kathleen E McKee, Miriam R Rafferty, Theadora W Sakata, David M Hedges, Garett J Griffith, Maddison M K Bingham, Stephanie A Obradovich, M Nicholas Francis, Daniel M Corcos

Abstract read
In one paragraph

Article in Frontiers in sports and active living, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Physical Activity and Exercise for People with Parkinson's Disease: The Past, Present, and Future.Movement disorders : official journal of the Movement Disorder Society · 2026
    Review
  2. Knee Health Is a Major Determinant of Mobility Across the Healthspan.Journal of functional morphology and kinesiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kathleen E McKeeDepartment of Neurology, Intermountain Medical Center Neurosciences Institute, Intermountain Health, Salt Lake City, UT, United States.
Miriam R Rafferty *Shirley Ryan AbilityLab, Chicago, IL, United States.
Theadora W Sakata *Department of Neurology, Intermountain Medical Center Neurosciences Institute, Intermountain Health, Salt Lake City, UT, United States.
David M HedgesDepartment of Analytics, Select Health, Salt Lake City, UT, United States.
Garett J GriffithDepartment of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL, United States.
Maddison M K BinghamDepartment of Neurology, Intermountain Medical Center Neurosciences Institute, Intermountain Health, Salt Lake City, UT, United States.
Stephanie A ObradovichNeurologic Physical Therapy, Intermountain Park City Hospital, Park City, UT, United States.
M Nicholas FrancisLifestyle Medicine and Wellness Center, Intermountain Park City Hospital, Park City, UT, United States.
Daniel M CorcosDepartment of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL, United States.

Funding

LeaRRN: the Learning Health Systems Rehabilitation Research NetworkP2CHD101895 · NICHD · BROWN UNIVERSITY · PI RESNIK, LINDA J. · 2020 to 2024
$6.4M
NICHD NIH HHS P2C HD101895
6 · The paper itself

Abstract

As Parkinson's disease (PD) progresses, relatively mild symptoms advance to a major disorder that affects every organ system in the body. Current care for people with PD (PwP) reacts to rising disability. There is a missed opportunity to keep PwP as healthy as possible. In this perspective, we spell out our vision for a proactive, value-based health care model built around a patient-centered integrated practice unit (IPU) for PD. The IPU will provide integrated interdisciplinary care overseen by a specialized Parkinson's primary care physician working closely with a movement disorders neurologist. The IPU will implement an evidence-based exercise program for people early in the disease. The focus of this intervention is a heart rate driven high-intensity aerobic exercise program, which is the only treatment with evidence that it can slow disease progression. It will also include resistance exercises, flexibility exercise and balance exercise. For people whose disease is moderate or severe, the IPU will provide care curated through a network of rehabilitation providers with expertise in PD all of whom understand the exercise prescription. By integrating care, slowing disease progression, and incorporating specialized rehabilitation we anticipate improving healthspan. In creating the IPU as a fully capitated (shared-risk) model in which the IPU and the insurance company assume joint accountability for quality and cost of care we anticipate demonstrating financial sustainability of implementing the exercise prescription and providing integrated care.

Indexed as

healthspanhigh-intensity aerobic exerciseintegrated practice unitParkinson's diseaseproactive care

Identifiers

PMID40529404
PMCPMC12171115

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.