ArticleFood science & nutrition2025
Oat Bran Hydrolysates Alleviate Oxidative Stress and Inflammation in d-Galactose-Induced Aging Mice.
Article in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Chondroitin sulfate modulates gut microbiota to improve bone metabolism and reduce locomotion problems in yellow-feathered broilers.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026Article
- Adipose-Derived Mesenchymal Stem Cells Alleviate ᴅ-Galactose-Induced Testicular Injury by Activating the Keap1/Nrf2 Pathway and Suppressing NLRP3-Associated Pyroptosis.Antioxidants (Basel, Switzerland) · 2026Article
- Interactions of Oat β-Glucan, Protein, and Starch Under High Hydrostatic Pressure and Their Influence on Starch Properties.Gels (Basel, Switzerland) · 2026Article
- Oat Bran Hydrolysates Alleviate Oxidative Stress and Inflammation in d-Galactose-Induced Aging Mice.Food science & nutrition · 2025Article
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Authors and funding
5 authors.
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Abstract
Oat bran hydrolysates exhibit various biological activities, including antioxidant and immunomodulation activities. Enzymatic hydrolysis can improve the antioxidant capacity of oat bran protein. In this study, Alcalase was used to hydrolyze oat bran protein and the resulting hydrolysates were separated by ultrafiltration, the antioxidant activity of fraction F1 (molecular weight > 10 kDa, OBH) was the highest in the four fractions, and selected for exploring the functional characteristics: d-galactose (d-gal; 300 mg/kg/day) induced aging of CL57BL/6J mice and OBH (200, 400, 800 mg/kg/day) intervened for 8 weeks. Normal mice were compared with aging mice induced by d-gal and aged mice treated with OBH. OBH intervention significantly improved the antioxidant oxidase activities in aging mice, such as total antioxidant capacity, catalase and glutathione peroxidase activities; it decreased malondialdehyde levels, and reduced the levels of tumor necrosis factor-α, interleukin (IL)-1β and IL-6 in the brain and serum. Pathological observations showed that OBH prevented brain damage. The results of high-throughput sequencing showed that the relative abundance of
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