Evidence map›Paper›PMID 40529861›Full record

ArticleSmall science2025

Exploring 2D Graphene-Based Nanomaterials for Biomedical Applications: A Theoretical Modeling Perspective.

Alexa Kamboukos, Nevena Todorova, Irene Yarovsky

Abstract read
In one paragraph

Article in Small science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alexa KamboukosSchool of Engineering RMIT University Melbourne Victoria 3001 Australia.ORCID https://orcid.org/0000-0001-8233-6920
Nevena TodorovaSchool of Engineering RMIT University Melbourne Victoria 3001 Australia.ORCID https://orcid.org/0000-0001-6358-2974
Irene YarovskySchool of Engineering RMIT University Melbourne Victoria 3001 Australia.ORCID https://orcid.org/0000-0002-4033-5150

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two-dimensional (2D) graphene-based nanomaterials (GNMs) have shown potential in biomedical applications, including diagnostics, therapeutics, and drug delivery, due to their unique combination of properties such as mechanical strength, excellent electrical and thermal conductivity as well as high adsorption capacity which, combined with the ease of their surface functionalization, enable biocompatibility and bioactivity. Theoretical molecular modeling can advance our understanding of the biomedical potential of 2D graphene-based nanomaterials by providing insights into the structure, dynamics, and interactions of these nanomaterials with biological systems, at the level of detail that experiments alone cannot currently access. This perspective highlights recent computational modeling advances and challenges in examining the interactions of 2D graphene-based nanomaterials with physiologically relevant biomolecular systems, including aqueous solutions, peptides, proteins, nucleic acids, lipid membranes, and pharmaceutical drug molecules. Examples of the theoretical contributions to design of graphene-based biomaterials and devices are also provided.

Indexed as

biomedicinegraphene nanomaterialsgraphene oxidemolecular simulationsnanotoxicity

Identifiers

PMID40529861
PMCPMC12168629

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.