Evidence map›Paper›PMID 40530083›Full record

ArticleInfectious medicine2025

Effect of glycemic control on lymphocyte subsets in the dissemination of pulmonary tuberculosis: A retrospective analysis.

Yujun Lin, Xiaohong Chen, Jiangwei Chen, Di Wu

Abstract read
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In one paragraph

Article in Infectious medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yujun LinDepartment of Respiratory and Critical Care Medicine, Fuzhou Pulmonary Hospital of Fujian Province, Fuzhou 350008, Fujian Province, China.
Xiaohong ChenDepartment of Tuberculosis, Fuzhou Pulmonary Hospital of Fujian Province, Fuzhou 350008, Fujian Province, China.
Jiangwei ChenThe Medical Services Section, Fuzhou Pulmonary Hospital of Fujian Province, Fuzhou 350008, Fujian Province, China.
Di WuDepartment of Tuberculosis, Fuzhou Pulmonary Hospital of Fujian Province, Fuzhou 350008, Fujian Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Extrapulmonary tuberculosis (EPTB) complicates pulmonary tuberculosis (PTB) management. Diabetes mellitus impairs immune function, worsening tuberculosis (TB) outcomes. Methods: This retrospective study investigates the effect of glycemic control on immune function and TB dissemination in 1,768 TB patients (2022-2024). Patients were stratified by glycated hemoglobin (HbA1c) levels (≤ 6% vs. > 6%) and fasting blood glucose (FBG) concentrations (< 7 vs. ≥ 7 mmol/L). Lymphocyte subsets (CD3 Results: Poor glycemic control was associated with lower cell counts of all lymphocyte subsets in patients with PTB (all Conclusions: Poor glycemic control impairs immune cells, while EPTB further reduces immune cell numbers. Integrated glycemic management and immunological monitoring help optimize treatment strategies and improve clinical outcomes, particularly in patients at risk for EPTB.

Indexed as

Extrapulmonary tuberculosisGlycated hemoglobinImmunityLymphocyte subpopulationPulmonary tuberculosis

Identifiers

PMID40530083
PMCPMC12173055

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.