ArticleCurrent clinical microbiology reports2024
Nutritional Immunity and Fungal Pathogens: a New Role for Manganese.
Article in Current clinical microbiology reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Invasive ambrosia beetles have zinc-enriched mandibles: support for the metal-prioritization hypothesis and insights into the mechanisms of metal deposition.Scientific reports · 2026Article
- Mechanisms and Therapeutic Potential of Nutritional Immunity.Pathogens (Basel, Switzerland) · 2026Review
- Manganese homeostasis modulates glucan and chitin unmasking in the opportunistic yeastVirulence · 2025Article
- Competition-Exclusion for Manganese Is Involved in Antifungal Activity of Two Lactic Acid Bacteria Against Various Dairy Spoilage Fungi.Microorganisms · 2025Article
- Associations Between Mineral Composition and Aflatoxin B1 in Maize (Foods (Basel, Switzerland) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Purpose of review: Copper, zinc, iron and manganese are essential micronutrients for all living organisms. Microbial pathogens must acquire these elements from their host. Through a process termed nutritional immunity, animal hosts seek to withhold these vital nutrients from the microbe and the competition for metals can influence survival outcomes during infection. Much is known about the battle for iron, copper and zinc during fungal infections, but a picture is just now beginning to emerge for manganese. Recent findings: Pathogenic fungi utilize manganese for antioxidant defense, cell wall construction, morphogenesis and survival in animal and plant hosts. The animal host can limit manganese availability for invading fungi at the macrophage, neutrophil and whole tissue levels.
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Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.