Evidence map›Paper›PMID 40530397›Full record

ReviewBiomedical reports2025

Therapies and nanotherapies for cervical cancer (Review).

Luz Victoria Sánchez-Meza, Ciresthel Bello-Rios, Yazmín Gómez-Gómez, Marco Antonio Leyva-Vázquez, Lilian Esmeralda Araujo-Arcos, José Alfredo Villanueva Duque, Jorge Organista-Nava, Berenice Illades-Aguiar

Abstract readReview
In one paragraph

Review in Biomedical reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Luz Victoria Sánchez-MezaLaboratory of Molecular Biomedicine, Faculty of Chemical Biological Sciences, Autonomous University of Guerrero, Chilpancingo, Guerrero 39090, Mexico.
Ciresthel Bello-RiosLaboratory of Molecular Biomedicine, Faculty of Chemical Biological Sciences, Autonomous University of Guerrero, Chilpancingo, Guerrero 39090, Mexico.
Yazmín Gómez-GómezLaboratory of Molecular Biomedicine, Faculty of Chemical Biological Sciences, Autonomous University of Guerrero, Chilpancingo, Guerrero 39090, Mexico.
Marco Antonio Leyva-VázquezLaboratory of Molecular Biomedicine, Faculty of Chemical Biological Sciences, Autonomous University of Guerrero, Chilpancingo, Guerrero 39090, Mexico.
Lilian Esmeralda Araujo-ArcosLaboratory of Molecular Biomedicine, Faculty of Chemical Biological Sciences, Autonomous University of Guerrero, Chilpancingo, Guerrero 39090, Mexico.
José Alfredo Villanueva DuqueMexican Social Security Institute, Family Medicine Unit No. 15, Clinical Coordination of Health Education and Research, Mexico City 04320, Mexico.
Jorge Organista-NavaLaboratory of Molecular Biomedicine, Faculty of Chemical Biological Sciences, Autonomous University of Guerrero, Chilpancingo, Guerrero 39090, Mexico.
Berenice Illades-AguiarLaboratory of Molecular Biomedicine, Faculty of Chemical Biological Sciences, Autonomous University of Guerrero, Chilpancingo, Guerrero 39090, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cervical cancer (CC) is a major global health concern, ranking fourth worldwide in mortality, due to its high death rate and strong link to persistent high-risk human papillomavirus infections, which drive cancer progression through cellular dysregulation. Conventional therapies used in the treatment of CC have significant disadvantages, such as adverse side effects that affect the quality of life of patients. These side effects may include nausea, vomiting, fatigue, hair loss, fertility problems, damage to nearby organs and systemic toxicity. To address these challenges, there has been an increased interest in using nanotechnology to improve CC therapy. Nanotechnology enables the targeted delivery of drugs or therapeutic agents directly to tumor cells, improving the bioavailability and stability of the treatment. In addition, nanomolecules can overcome biological barriers to ensure precise delivery of drugs to targeted tissues. Currently, several delivery nanosystems enable the transport of drugs to their target sites without altering their composition and preventing them from being degraded. Extensive research has demonstrated the benefits of applying nanotechnology in targeted therapies for different cancer types, seeking to overcome the limitations of conventional therapies and allowing more precise and effective administration of treatments. Therefore, the present review highlights promising nanoparticles used to specifically target CC cells, aiming to enhance the effectiveness of treatment and reduce side effects, thus improving the quality of life of patients.

Indexed as

cervical cancerhigh-risk HPVnanotechnologytargered therapeutics

Identifiers

PMID40530397
PMCPMC12171687

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.