Evidence map›Paper›PMID 40530669›Full record

SynthesisHead & neck2025

A Systematic Review of the Clinical Impact of Implementing Artificial Intelligence in Upper Aerodigestive Tract Endoscopy.

Celine M L H Wilmes, Arsen Goril BSc, Henri A M Marres, David J Wellenstein, Guido B van den Broek

Abstract readSystematic Review
In one paragraph

Synthesis in Head & neck, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Videomics and artificial intelligence in endoscopic diagnosis of laryngeal lesions: mapping current evidence through a scoping review.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2026
    Review
  4. Multicenter Clinical Validation of an Artificial Intelligence Diagnostic Classification Model for Laryngoscopy Images.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Celine M L H WilmesDepartment of Otorhinolaryngology and Head and Neck Surgery, Radboud University Medical Center, Nijmegen, the Netherlands.ORCID 0009-0008-8274-6274
Arsen Goril BScDepartment of Otorhinolaryngology and Head and Neck Surgery, Radboud University Medical Center, Nijmegen, the Netherlands.
Henri A M MarresDepartment of Otorhinolaryngology and Head and Neck Surgery, Radboud University Medical Center, Nijmegen, the Netherlands.
David J WellensteinDepartment of Otorhinolaryngology and Head and Neck Surgery, Rijnstate Hospital, Arnhem, the Netherlands.ORCID 0000-0002-8437-5664
Guido B van den BroekDepartment of Otorhinolaryngology and Head and Neck Surgery, Radboud University Medical Center, Nijmegen, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEndoscopy is essential in upper aerodigestive tract (UADT) examination, particularly in the early detection of laryngopharyngeal lesions. However, UADT endoscopy remains operator-dependent and lacks standardized quality metrics. Recent advancements in artificial intelligence (AI) have generated interest in applications within UADT endoscopy. This review evaluates the clinical impact of AI in UADT endoscopy.

methodsA literature review was conducted up to December 31, 2024. Studies were evaluated using the modified Quality Assessment of Diagnostic Accuracy Studies (QUADAS)-2 tool.

resultsEighty-three studies were included. Results indicate that AI in UADT endoscopy achieves diagnostic accuracy, sensitivity, and specificity rates comparable to experts, with optimal outcomes combined with human expertise. AI also demonstrated significantly faster inference times.

conclusionsThis review highlights AI's potential to enhance clinical impact in UADT endoscopy, especially when combined with human expertise. However, the limited focus on real-time clinical translation underscores the need for further research to enable effective integration into clinical practice.

Indexed as

Artificial IntelligenceEndoscopyHumansSensitivity and Specificityartificial intelligencedeep learningendoscopymachine learningupper aerodigestive tract

Identifiers

PMID40530669
PMCPMC12541685

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.