ReviewMicroRNA (Shariqah, United Arab Emirates)2025
MicroRNA: A Novel Class of Potential Biomarkers and Therapeutic Target for Non-Alcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis.
Review in MicroRNA (Shariqah, United Arab Emirates), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Non-alcoholic fatty liver disease (NAFLD) is commonly related to metabolic-associated chronic liver disease, which has a pathological spectrum from simple steatosis to non-alcoholic steatohepatitis (NASH), fibrosis, cirrhosis, and hepatocellular carcinoma (HCC). It is mainly associated with other disease conditions, such as obesity, type 2 diabetes mellitus (T2DM), and cardiovascular disease. MicroRNAs (miRs) are small non-coding RNAs, having 22 nucleotides in length, that play an important role in epigenetic modulation for disease. miRs act by targeting mRNA and altering its expression. Alteration of miRs regulates different stages of NAFLD and NASH. A liver biopsy is the gold standard diagnosis for NASH. However, it is an invasive diagnostic process, so it is not feasible to screen a large number of NASH patients. Consequently, it is imperative to develop new non-invasive diagnosis strategies to detect NAFLD to NASH progression. Circulating miR can be a novel diagnostic marker for NAFLD/NASH. This review explains the role of miRs in the pathogenesis and miR-based targeted therapy in NAFLD/NASH.
Indexed as
Identifiers
40530720What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.