Evidence map›Paper›PMID 40530996›Full record

ArticleAntimicrobial agents and chemotherapy2025

Synergistic antibacterial activity and prevention of drug resistance of daptomycin combined with fosfomycin against methicillin-resistant

Qin Ai, Sailan Wang, Ziyan Chen, Shuai Zheng, Zaixing Chen, Na Zhang, Yaowen Li, Huiping Liu, Yanyan Liu, Jiabin Li and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Qin AiDepartment of Basic and Clinical Pharmacology, School of Pharmaceutical Sciences, Anhui Medical University, Hefei, China.
Sailan WangDepartment of Basic and Clinical Pharmacology, School of Pharmaceutical Sciences, Anhui Medical University, Hefei, China.
Ziyan ChenDepartment of Basic and Clinical Pharmacology, School of Pharmaceutical Sciences, Anhui Medical University, Hefei, China.
Shuai ZhengDepartment of Basic and Clinical Pharmacology, School of Pharmaceutical Sciences, Anhui Medical University, Hefei, China.
Zaixing ChenDepartment of Basic and Clinical Pharmacology, School of Pharmaceutical Sciences, Anhui Medical University, Hefei, China.
Na ZhangDepartment of Basic and Clinical Pharmacology, School of Pharmaceutical Sciences, Anhui Medical University, Hefei, China.ORCID 0000-0002-0057-4907
Yaowen LiDepartment of Basic and Clinical Pharmacology, School of Pharmaceutical Sciences, Anhui Medical University, Hefei, China.
Huiping LiuDepartment of Basic and Clinical Pharmacology, School of Pharmaceutical Sciences, Anhui Medical University, Hefei, China.
Yanyan LiuDepartment of Infectious Diseases & Anhui Center for Surveillance of Bacterial Resistance, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Jiabin LiDepartment of Infectious Diseases & Anhui Center for Surveillance of Bacterial Resistance, The First Affiliated Hospital of Anhui Medical University, Hefei, China.ORCID 0000-0002-6539-1802
Xiaohui HuangDepartment of Basic and Clinical Pharmacology, School of Pharmaceutical Sciences, Anhui Medical University, Hefei, China.ORCID 0000-0002-4768-9103

Funding

National Natural Science Foundation of China 81173133
6 · The paper itself

Abstract

The combination of daptomycin and fosfomycin is attracting attention due to the rising resistance observed in methicillin-resistant

Indexed as

Anti-Bacterial AgentsDaptomycinFosfomycinMethicillin-Resistant Staphylococcus aureusBiofilmsDrug Resistance, Multiple, BacterialDrug SynergismHumansMicrobial Sensitivity TestsMutationStaphylococcal InfectionsAnti-Bacterial AgentsDaptomycinFosfomycinantibiotics resistancedaptomycinfosfomycinmethicillin-resistant Staphylococcus aureus

Identifiers

PMID40530996
PMCPMC12327001

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.