Evidence mapPaperPMID 40532137Full record

ReviewJCO global oncology2025

Emerging Trends in Point-of-Care Technology Development for Oncology in Low- and Middle-Income Countries.

Wenting Gao, Jason C Manning, Kirtana Devaraj, Rebecca R Richards-Kortum, Sally M McFall, Robert L Murphy, Aggrey Semeere, David Erickson

Abstract readReview
In one paragraph

Review in JCO global oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wenting GaoMeinig School of Biomedical Engineering, Cornell University, Ithaca, NY.ORCID 0009-0005-2356-5244
Jason C ManningMeinig School of Biomedical Engineering, Cornell University, Ithaca, NY.ORCID 0000-0002-6839-382X
Kirtana DevarajMeinig School of Biomedical Engineering, Cornell University, Ithaca, NY.ORCID 0009-0007-0057-4345
Rebecca R Richards-KortumDepartment of Bioengineering, Rice University, Houston, TX.ORCID 0000-0003-2347-9467
Sally M McFallDepartment of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, IL.ORCID 0000-0001-5554-6615
Robert L MurphyDepartment of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, IL.ORCID 0000-0003-3936-2052
Aggrey SemeereInfectious Diseases Institute, Makerere University College of Health Sciences, Kampala, Uganda.ORCID 0000-0003-1826-2239
David EricksonSibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY.ORCID 0000-0002-1624-9711

Funding

The Center for Innovation in Point-of-Care Technologies for HIV/AIDS and Emerging Infectious Diseases at Northwestern University (C-THAN)U54EB027049 · NORTHWESTERN UNIVERSITY · 2025 to 2025
$1.6M
Technology CoreU54EB034654 · CORNELL UNIVERSITY · 2025 to 2025
$1.3M
The Center for Innovation and Translation of Point of Care Technologies for Expanded Cancer Care Access (CITEC)U54EB034652 · RICE UNIVERSITY · 2025 to 2025
$1.3M
NIBIB NIH HHS U54 EB027049NIBIB NIH HHS U54 EB034652NIBIB NIH HHS U54 EB034654
6 · The paper itself

Abstract

The growing cancer burden and suboptimal diagnostic capacity in low- and middle-income countries calls for urgent innovation in diagnostic solutions. Point-of-care technologies (POCTs) offer a transformative approach to decentralizing cancer diagnostics by providing rapid, affordable, and scalable testing in resource-constrained settings. Recent advancements, including loop-mediated isothermal amplification and multiplexed lateral flow immunoassay, enable high-sensitivity detection of cancer biomarkers without the need for complex laboratory infrastructure. Additionally, noninvasive imaging tools, such as optical coherence tomography and fluorescence-guided microscopy, offer portable and cost-effective solutions for early cancer detection in settings with limited health care services. These innovations are complemented by the integration of artificial intelligence, which improves diagnostic accuracy and reduces reliance on highly trained personnel. However, significant infrastructure and logistical challenges persist, including resource constraints, unreliable electricity, and insufficient cold-chain logistics, which limit diagnostic precision and accessibility. This review discusses recent advances in POCTs for oncology and examines how public-private partnerships and multisector collaborations can address key implementation barriers. By prioritizing inclusivity, cross-sector collaboration, and targeted investments, POCTs can sustainably narrow global disparities in cancer diagnosis and treatment.

Indexed as

Medical OncologyNeoplasmsPoint-of-Care SystemsDeveloping CountriesHumans

Identifiers

PMID40532137
PMCPMC12312415

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.