Evidence map›Paper›PMID 40533083›Full record

ArticleInfluenza and other respiratory viruses2025

COVID-19 Hospitalizations, Vaccine Uptake, Vaccination Guidelines, and Vaccine Availability in Six Middle-Income Countries and Areas in Europe, May 2022-April 2024.

Erin Rachel Whitehouse, Paul Elish, Elona Kureta, Dragan Kochinski, Dragana Plavsa, Giorgi Chakhunashvili, Besfort Kryeziu, Sayragul Abdyldaeva, Miguel Angel Sanchez Ruiz, Sandra Cohuet and 13 more

Abstract read
In one paragraph

Article in Influenza and other respiratory viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Erin Rachel WhitehouseUnited States Centers for Disease Control and Prevention, Atlanta, Georgia, USA.ORCID 0000-0002-5158-0282
Paul ElishUnited States Centers for Disease Control and Prevention, Atlanta, Georgia, USA.ORCID 0000-0002-1155-950X
Elona KuretaInstitute of Public Health, Tirana, Albania.
Dragan KochinskiInstitute of Public Health, Skopje, Republic of North Macedonia.
Dragana PlavsaNational Institute of Public Health, Belgrade, Serbia.
Giorgi ChakhunashviliNational Center for Disease Control and Public Health, Tbilisi, Georgia, USA.
Besfort KryeziuNational Institute of Public Health, Pristina, Kosovo.ORCID 0000-0002-9529-0770
Sayragul AbdyldaevaDepartment for Disease Prevention and State Sanitary and Epidemiological Surveillance, Bishkek, Kyrgyzstan.
Miguel Angel Sanchez RuizEpiconcept, Paris, France.
Sandra CohuetEpiconcept, Paris, France.
James HumphreysEpiconcept, Paris, France.ORCID 0009-0004-3789-8309
Kujtim MersiniFaculty of Veterinary Medicine, Agricultural University of Tirana, Tirana, Albania.
Oksana ArtemchukWorld Health Organization Regional Office for Europe, Copenhagen, Denmark.
Maja StosicNational Institute of Public Health, Belgrade, Serbia.
Olgha Tarkhan-MouraviNational Center for Disease Control and Public Health, Tbilisi, Georgia, USA.
Ariana KalaveshiNational Institute of Public Health, Pristina, Kosovo.
Dinagul OtorbaevaDepartment for Disease Prevention and State Sanitary and Epidemiological Surveillance, Bishkek, Kyrgyzstan.
Kristina StavridisInstitute of Public Health, Skopje, Republic of North Macedonia.
Silvia BinoInstitute of Public Health, Tirana, Albania.
Marc-Alain WiddowsonWorld Health Organization Regional Office for Europe, Copenhagen, Denmark.
Eva LeidmanUnited States Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Iris FinciWorld Health Organization Regional Office for Europe, Copenhagen, Denmark.
Mark A KatzWorld Health Organization Regional Office for Europe, Copenhagen, Denmark.ORCID 0000-0002-5532-7276

Funding

US Centers for Disease Control and PreventionWorld Health Organization 001World Health Organization, Regional Office for Europe
6 · The paper itself

Abstract

backgroundUpdated regional data on COVID-19 epidemiology and vaccination can inform vaccine policies and implementation strategies.

methodsWe used surveillance data on patients hospitalized from the European SARI Vaccine Effectiveness (EuroSAVE) network to describe COVID-19 epidemiology and COVID-19 vaccine uptake among adults hospitalized with severe acute respiratory infection (SARI) in six middle-income countries and areas (CAs) in the WHO European region during 2022-2024. For SARI patients, we collected data on demographics, comorbidities, vaccination status, and hospital course, and a respiratory specimen, which was tested for SARS-CoV-2 by RT-PCR. In October 2024, we surveyed national public health institute staff on national COVID-19 vaccine guidelines and availability.

resultsOf SARI patients, 833/3982 (20.9%) and 367/3752 (9.8%) tested positive for SARS-CoV-2 during May 2022-April 2023 and May 2023-April 2024, respectively. Of COVID-19 patients, 857 (71.4%) were ≥60 years old and 713 (59.4%) had ≥1 comorbidity. A higher proportion of COVID-19 patients required mechanical ventilation (30 [8.2%] vs. 23 [2.8%], p <0.001) and intensive care (70 [8.4%] vs. 48 [13.1%], p =0.016) during May 2023-April 2024 compared to May 2022-April 2023. COVID-19 vaccination in the last 12 months decreased from 25% in 2022-2023 to 3% in 2023-2024. Most CAs had not updated their COVID-19 vaccination guidelines to recommend annual vaccination, and only two had vaccines available.

conclusionsAlthough COVID-19 was associated with severe disease among SARI patients, COVID-19 vaccination uptake was low among priority populations recommended for vaccination by WHO guidance. Continued efforts to understand reasons for low vaccine uptake and improve vaccine access will help protect those at greatest risk for COVID-19-associated morbidity and mortality.

Indexed as

COVID-19COVID-19 VaccinesHospitalizationVaccinationVaccination CoverageAdolescentAdultAgedEuropeFemaleHumansMaleMiddle AgedSARS-CoV-2Young AdultCOVID-19 VaccinesCOVID‐19 epidemiologyCOVID‐19 vaccinesCOVID‐19 virus disease

Identifiers

PMID40533083
PMCPMC12176449

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.