Evidence mapPaperPMID 40533747Full record

ArticleNutrition journal2025

Joint association of the newly proposed dietary index for gut microbiota and sleep disorders with survival among US adult population with diabetes and pre-diabetes.

Ke Si, Chuanqin Shi, Yajing Huang, Chuanfeng Liu, Jingwei Chi, Lili Xu, Ying Chen, Yangang Wang

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Article in Nutrition journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Ke SiDepartment of Endocrinology, Affiliated Hospital of Qingdao University, Qingdao, 266003, China.
Chuanqin ShiMarine Biomedical Research Institute of Qingdao, School of Medicine and Pharmacy, Key Laboratory of Marine Drugs, Chinese Ministry of Education, Ocean University of China, Qingdao, 266003, China.
Yajing HuangDepartment of Endocrinology, Affiliated Hospital of Qingdao University, Qingdao, 266003, China.
Chuanfeng LiuDepartment of Endocrinology, Affiliated Hospital of Qingdao University, Qingdao, 266003, China.
Jingwei ChiDepartment of Endocrinology, Affiliated Hospital of Qingdao University, Qingdao, 266003, China.
Lili XuDepartment of Endocrinology, Affiliated Hospital of Qingdao University, Qingdao, 266003, China.
Ying ChenDepartment of Endocrinology, Affiliated Hospital of Qingdao University, Qingdao, 266003, China.
Yangang WangDepartment of Endocrinology, Affiliated Hospital of Qingdao University, Qingdao, 266003, China. wangyg1966@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiet and sleep disorders are associated with risks of metabolic diseases such as diabetes. The dietary index for gut microbiota (DI-GM) is a newly proposed index designed to assess dietary quality associated with maintaining a healthy gut microbiota. The authors aim to investigate the separate and joint prognostic effect of DI-GM and sleep disorders on the survival of US population with diabetes and pre-diabetes.

methodsData were from the National Health and Nutrition Examination Survey (NHANES) 2007-2018 at baseline linked to the 2019 National Death Index records. Dietary recall data were collected to calculate the DI-GM and sleep disorders were assessed by self-reported questionnaires. The Cox proportional hazard model were used to evaluate the associations between separate and joint prognostic effects of DI-GM and sleep disorders with mortality outcomes among diabetic and pre-diabetic patients.

resultsA total of 10718 Participants with diabetes and pre-diabetes were ultimately included in this study (weighted population: 67,232,394, weighted mean age [SE]: 57.0 [0.1] years; weighted female proportion: 51.8%). Among these participants, higher DI-GM was more prevalent in those without sleep disorders. During the median follow-up of 13.3 years, 1448 deaths occurred, including 346 participants died from cancer, and 367 died from cardiovascular disease (CVD)..Multivariable models indicated that the joint effects of DI-GM (≥ 6) and no sleep disorders were associated with lower risks for all-cause (HR 0.53, 95% CI: 0.38-0.79) and CVD mortality (HR 0.36, 95% CI: 0.19-0.65).

conclusionsIn a nationally representative sample of US population with diabetes and pre-diabetes, high DI-GM combined with no sleep disorders was associated with significantly reduced all-cause and CVD mortality risks.

Indexed as

Diabetes MellitusDietGastrointestinal MicrobiomePrediabetic StateSleep Wake DisordersAdultAgedFemaleHumansMaleMiddle AgedNutrition SurveysProportional Hazards ModelsUnited StatesDI-GMJoint associationNHANESSleep disordersSurvival

Identifiers

PMID40533747
PMCPMC12175418

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.