Evidence map›Paper›PMID 40534199›Full record

ArticleNano letters2025

Diamond Molecular Balance: Ultra-Wide Range Nanomechanical Mass Spectrometry from MDa to TDa.

Donggeun Lee, Seung-Woo Jeon, Chang-Hwan Yi, Yanghee Kim, Yeeun Choi, Sang-Hun Lee, Jinwoong Cha, Seung-Bo Shim, Junho Suh, Il-Young Kim and 7 more

Abstract read
In one paragraph

Article in Nano letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Donggeun LeeCenter for Quantum Technology, Korea Institute of Science and Technology (KIST), Seoul 02792, Republic of Korea.ORCID 0000-0003-1994-1540
Seung-Woo JeonCenter for Quantum Technology, Korea Institute of Science and Technology (KIST), Seoul 02792, Republic of Korea.
Chang-Hwan YiCenter for Theoretical Physics of Complex Systems, Institute for Basic Science (IBS), Daejeon 34126, Republic of Korea.
Yanghee KimAdvanced Analysis and Data Center, Korea Institute of Science and Technology, Seoul 02792, South Korea.
Yeeun ChoiCenter for Quantum Technology, Korea Institute of Science and Technology (KIST), Seoul 02792, Republic of Korea.
Sang-Hun LeeDepartment of Optical Engineering, Kumoh National Institute of Technology, Gumi, Gyoungbuk 39235, Republic of Korea.ORCID 0000-0002-0830-7862
Jinwoong ChaQuantum Technology Institute, Korea Research Institute of Standards and Science, Daejeon 34113, Republic of Korea.ORCID 0000-0002-1380-4345
Seung-Bo ShimQuantum Technology Institute, Korea Research Institute of Standards and Science, Daejeon 34113, Republic of Korea.
Junho SuhDepartment of Physics, Pohang University of Science and Technology (POSTECH), Pohang 37673, Republic of Korea.
Il-Young KimCenter for Quantum Technology, Korea Institute of Science and Technology (KIST), Seoul 02792, Republic of Korea.
Dongyeon Daniel KangCenter for Quantum Technology, Korea Institute of Science and Technology (KIST), Seoul 02792, Republic of Korea.
Hojoong JungCenter for Quantum Technology, Korea Institute of Science and Technology (KIST), Seoul 02792, Republic of Korea.ORCID 0000-0001-7059-1713
Cherlhyun JeongChemical and Biological Integrative Research Center, Korea Institute of Science and Technology, Seoul 02792, Republic of Korea.
Jae-Pyoung AhnAdvanced Analysis and Data Center, Korea Institute of Science and Technology, Seoul 02792, South Korea.ORCID 0000-0003-2657-7425
Hee Chul ParkDepartment of Physics, Pukyong National University, Busan 48513, Republic of Korea.
Sang-Wook HanCenter for Quantum Technology, Korea Institute of Science and Technology (KIST), Seoul 02792, Republic of Korea.
Chulki KimCenter for Quantum Technology, Korea Institute of Science and Technology (KIST), Seoul 02792, Republic of Korea.ORCID 0000-0002-9806-5122

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The significance of mass spectrometry lies in its unparalleled ability to accurately identify and quantify molecules in complex samples, providing invaluable insights into molecular structures and interactions. Here, we leverage diamond nanostructures as highly sensitive mass sensors by utilizing a self-excitation mechanism under an electron beam in a conventional scanning electron microscope (SEM). The diamond molecular balance (DMB) exhibits a practical mass resolution of 4.07 MDa, based on its notable mechanical quality factor and frequency stability, along with a broad dynamic range from MDa to TDa. This positions the DMB at the forefront of nanoelectromechanical system (NEMS)-based mass spectrometry operating at room temperature. Notably, the DMB demonstrated its ability to measure the mass of a single bacteriophage T4 by precisely locating the analyte on the device. These findings demonstrate the capability and potential of the DMB as a revolutionary tool for mass spectrometry at room temperature.

Indexed as

Bacteriophage T4DiamondMass SpectrometryMultiplexing4Nanoelectromechanical Systems

Identifiers

PMID40534199
PMCPMC12232386

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.