Evidence map›Paper›PMID 40534570›Full record

ArticleACS biomaterials science & engineering2025

Greener Decellularization of Porcine Auricular Cartilage Using Supercritical Technology and Different Pretreatments for Application in Tissue Engineering.

Victor M de Souza, Carolina C Zuliani, Jéssica B da Cunha, Juliana Carron, Carmen S P Lima, Ibsen B Coimbra, Paulo T V Rosa, Ângela M Moraes

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS biomaterials science & engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Victor M de SouzaSchool of Chemical Engineering, University of Campinas - UNICAMP, 13083-852 Campinas, São Paulo, Brazil.ORCID 0000-0002-7193-4017
Carolina C ZulianiSchool of Medical Sciences, University of Campinas - UNICAMP, 13083-887 Campinas, São Paulo, Brazil.
Jéssica B da CunhaSchool of Medical Sciences, University of Campinas - UNICAMP, 13083-887 Campinas, São Paulo, Brazil.
Juliana CarronSchool of Medical Sciences, University of Campinas - UNICAMP, 13083-887 Campinas, São Paulo, Brazil.
Carmen S P LimaSchool of Medical Sciences, University of Campinas - UNICAMP, 13083-887 Campinas, São Paulo, Brazil.
Ibsen B CoimbraSchool of Medical Sciences, University of Campinas - UNICAMP, 13083-887 Campinas, São Paulo, Brazil.
Paulo T V RosaInstitute of Chemistry, University of Campinas - UNICAMP, 13083-970 Campinas, São Paulo, Brazil.
Ângela M MoraesSchool of Chemical Engineering, University of Campinas - UNICAMP, 13083-852 Campinas, São Paulo, Brazil.ORCID 0000-0002-5813-332X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Scaffolds for tissue engineering can be obtained from synthetic or natural materials, with decellularized tissues being particularly attractive. Among these, porcine auricular cartilage is of special interest because of its availability, similarity to the human extracellular matrix (ECM), and cost-effectiveness. Decellularization of animal tissues yields extracellular matrices (ECM) rich in collagen, elastin, and glycosaminoglycans (GAGs), which are essential for providing mechanical support and creating a favorable environment for cell adhesion and tissue development. Traditional decellularization methods that rely on surfactants, such as sodium dodecyl sulfate (SDS), can have drawbacks, including protein denaturation, cytotoxic effects, the need for extensive washing, and the production of hazardous effluents. Alternative approaches involving the use of supercritical CO

Indexed as

Decellularized Extracellular MatrixEar CartilageTissue EngineeringAnimalsCarbon DioxideExtracellular MatrixGlycosaminoglycansSodium Dodecyl SulfateSwineTissue ScaffoldsCarbon DioxideDecellularized Extracellular MatrixGlycosaminoglycansSodium Dodecyl Sulfatedecellularizationextractionfreeze−thawosmotic shockporcine auricular cartilagescaffoldsupercritical fluidtissue engineering

Identifiers

PMID40534570
PMCPMC12264865

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.