Evidence map›Paper›PMID 40534679›Full record

ArticleACS pharmacology & translational science2025

Tyrosine Peptides Alleviates Multifaceted Toxicity Linked to Expanded CGG Repeats in Fragile X‑Associated Tremor/Ataxia Syndrome.

Krishna Singh, Sakshi Shukla, Tapas Ghosh, Apurba K Das, Amit Kumar

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS pharmacology & translational science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Krishna SinghDepartment of Biosciences and Biomedical Engineering, Indian Institute of Technology Indore, Simrol, Indore 453552, India.
Sakshi ShuklaDepartment of Biosciences and Biomedical Engineering, Indian Institute of Technology Indore, Simrol, Indore 453552, India.
Tapas GhoshDepartment of Chemistry, Indian Institute of Technology Indore, Simrol, Indore 453552, India.ORCID https://orcid.org/0000-0002-0256-2467
Apurba K DasDepartment of Chemistry, Indian Institute of Technology Indore, Simrol, Indore 453552, India.ORCID https://orcid.org/0000-0002-8141-6854
Amit KumarDepartment of Biosciences and Biomedical Engineering, Indian Institute of Technology Indore, Simrol, Indore 453552, India.ORCID https://orcid.org/0000-0002-5913-4308

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fragile X-associated Tremor/Ataxia Syndrome (FXTAS)/Fragile X-associated Primary Ovarian Insufficiency (FXPOI) are conditions caused by an elevated level of CGG repeats in the 5' untranslated region (5'-UTR) of the Fragile X Mental Retardation 1 (FMR1) gene. These trinucleotide extended RNA repeats [r-(CGG)

Indexed as

FMR1poly-GFXTAS/FXPOIhomoaromatic tyrosine-based peptidesr(CGG)exprepeat-associated non-ATG (RAN)trinucleotide repeats

Identifiers

PMID40534679
PMCPMC12171881

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.