Evidence mapPaperPMID 40535039Full record

ReviewFrontiers in nutrition2025

Sex differences in ketogenic diet: are men more likely than women to lose weight?

Yingying Jiao, Xiuru Chen, Lu Liu, Yantong Lu, Minghuang Gao, Qi Wang, Xiaoling Chi, Yousheng Mo

Abstract readReview
In one paragraph

Review in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. A ketogenic diet reduces hepatic alcohol metabolism and alcohol consumption in rats.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Review
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  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yingying JiaoScience and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Xiuru ChenScience and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Lu LiuScience and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Yantong LuScience and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Minghuang GaoScience and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Qi WangScience and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Xiaoling ChiDepartment of Hepatology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, Guangdong, China.
Yousheng MoDepartment of Hepatology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As economy is growing, the number of patients living with obesity has rapidly increased globally. Patients with obesity or diabetes have become a serious global health issue that requires the attention and participation of society as a whole. The ketogenic diet, as an emerging nutritional therapy for improving obesity, takes into consideration the differences between sexes in genetic variation, hormonal balance, and body fat distribution. The aim is to elucidate the effectiveness of sex differences in ketogenic dieting for weight loss and to explore suitable weight loss strategies. In this review, we delve into the physiological sexual differences between men and women in terms of fat and muscle tissue and discuss the sex-specific potential mechanisms underlying the differential effects of the ketogenic diet for weight loss. Based on this foundation, we further propose brief weight loss recommendations beneficial for both men and women. It is hoped that, in this direction, the optimization of short-term or long-term clinical weight loss programs can be developed based on sexes.

Indexed as

ketogenic dietmechanismmetabolismobesitysex differences

Identifiers

PMID40535039
PMCPMC12173872

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.