Evidence mapPaperPMID 40535104Full record

ReviewOncology letters2025

Treatment of ovarian cancer: From the past to the new era (Review).

Khaled Alrosan, Amjad Z Alrosan, Ghaith B Heilat, Alaa F Alrousan, Omar S Gammoh, Abdelrahim Alqudah, Saba Madae'En, Mohammed J Alrousan

Abstract readReview
In one paragraph

Review in Oncology letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. m6A modification and its clinical applications in gynaecological cancer.Apoptosis : an international journal on programmed cell death · 2026
    Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Khaled AlrosanDepartment of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmaceutical Sciences, The Hashemite University, Zarqa 13133, Jordan.
Amjad Z AlrosanDepartment of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmaceutical Sciences, The Hashemite University, Zarqa 13133, Jordan.
Ghaith B HeilatDepartment of General Surgery and Urology, Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan.
Alaa F AlrousanFaculty of Pharmacy, Jordan University of Science and Technology, Irbid 22110, Jordan.
Omar S GammohDepartment of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmacy, Yarmouk University, Irbid 21163, Jordan.
Abdelrahim AlqudahDepartment of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmaceutical Sciences, The Hashemite University, Zarqa 13133, Jordan.
Saba Madae'EnDepartment of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmaceutical Sciences, The Hashemite University, Zarqa 13133, Jordan.
Mohammed J AlrousanDepartment of General surgery, King Fahad Specialist Hospital, Tabuk 47717, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ovarian cancer is the most lethal malignancy among female genital cancers, primarily due to the non-specific symptoms, late-stage diagnosis and poor prognosis. Thus, there is a need for accurate and precise diagnostic methods to improve overall survival rates. The aim of the present review was to provide a comprehensive overview of ovarian cancer, including its epidemiology, clinical presentation, etiology, risk factors, staging and diagnostic techniques, in addition to examining the therapeutic approaches, including cytoreductive surgery and adjuvant treatments, while highlighting the mechanisms of resistance to such interventions. Advancements in molecular profiling and a deeper understanding of ovarian tumorigenesis have led to the introduction of novel therapeutic agents currently in clinical use or under clinical investigation. These innovations may improve the management of ovarian cancer, potentially improving survival outcomes.

Indexed as

chemotherapyovarian cancerre-purposing therapyresistancetargeted therapy

Identifiers

PMID40535104
PMCPMC12174768

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.