Evidence map›Paper›PMID 40535387›Full record

ReviewCureus2025

The Efficacy of Ayurvedic Herbs in the Prevention and Treatment of Inflammatory Bowel Disease: A Scoping Review.

Sakshika Vakiti, Lessie Farriss, Hasrat Mehta, Meghana Madaram, Diana Ferrigno, Rita Shoukry, Jessica Arango Hipsley, Bona Lee, Lian Atlas-Grayton, Celia Carlisano and 1 more

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sakshika VakitiOsteopathic Medical School, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Clearwater, USA.
Lessie FarrissOsteopathic Medical School, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Clearwater, USA.
Hasrat MehtaOsteopathic Medical School, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Clearwater, USA.
Meghana MadaramOsteopathic Medical School, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Clearwater, USA.
Diana FerrignoOsteopathic Medical School, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Clearwater, USA.
Rita ShoukryOsteopathic Medical School, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Clearwater, USA.
Jessica Arango HipsleyOsteopathic Medical School, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Clearwater, USA.
Bona LeeOsteopathic Medical School, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Clearwater, USA.
Lian Atlas-GraytonOsteopathic Medical School, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Clearwater, USA.
Celia CarlisanoOsteopathic Medical School, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Clearwater, USA.
Stephanie N PetroskyNutrition, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Clearwater, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory bowel disease (IBD) is a chronic inflammatory condition of the gastrointestinal tract with no known cure in Western medicine. While steroids and other anti-inflammatory treatments help manage symptoms, Ayurvedic herbs and spices offer a holistic approach rooted in Ayurveda, an ancient Indian medical system that aims to balance life's forces (doshas) within the mind, body, and soul. Although certain Ayurvedic herbs have demonstrated anti-inflammatory properties, a comprehensive review of their efficacy in IBD treatment remains limited. This study evaluates the effectiveness of Ayurvedic herbal extracts and formulations in the treatment and prevention of IBD through a review of literature from January 2003 to September 2023 across Embase, PubMed, and Cochrane Central. A total of 25 full-text articles were analyzed, with data compiled based on study characteristics and relevance to the research question. Findings indicate macroscopic, microscopic, and clinically significant benefits, including reduced mucus in stool, improved colonic weight retention, and decreased inflammatory markers such as tumor necrosis factor-α (TNF-α), interleukin-2 (IL-2), prostaglandin E2 (PGE2), and endothelium-dependent relaxation (EDR). Clinically, patients reported fewer urgent bowel movements and an improved sense of well-being. These results suggest that Ayurvedic herbs may serve as a complementary or alternative therapy for IBD, warranting further well-designed clinical trials to fully assess their therapeutic potential.

Indexed as

ayurvedacolitiscrohn’sherbsinflammatory bowel disease

Identifiers

PMID40535387
PMCPMC12176073

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.