Evidence map›Paper›PMID 40535500›Full record

ReviewWorld journal of transplantation2025

Current concepts and recent trends in endothelial keratoplasty.

Prateek Nishant, Bharat Gurnani, Prabhakar Singh, Sony Sinha, Kirandeep Kaur, Ashish Kumar, Ranjeet Kumar Sinha

Abstract readReview
In one paragraph

Review in World journal of transplantation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Protocol for Cryopreservation of Endothelial Monolayers: An Update.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Prateek NishantDepartment of Ophthalmology-Refractive Surgery, Uvea and Neuro-Ophthalmology, Akhand Jyoti Eye Hospital, Mastichak, Saran 841219, Bihar, India.
Bharat GurnaniDepartment of Cataract, Cornea, External Diseases, Trauma, Ocular Surface, Refractive Surgery and Contact Lens, Gomabai Netralaya and Research Center, Neemuch 458441, Madhya Pradesh, India.
Prabhakar SinghDepartment of Ophthalmology-Cornea and Ocular Surface, All India Institute of Medical Sciences, Kalyani 741245, West Bengal, India.
Sony SinhaDepartment of Ophthalmology-Vitreo-Retina, Neuro-Ophthalmology and Oculoplasty, All India Institute of Medical Sciences, Patna 801507, Bihar, India. nishanteyecare@gmail.com.
Kirandeep KaurDepartment of Cataracts, Pediatric Ophthalmology and Strabismus, Gomabai Netralaya and Research Center, Neemuch 458441, Madhya Pradesh, India.
Ashish KumarDepartment of Cornea and Refractive Surgery, Laxmi Netralaya, Jamal Road, Patna 800001, Bihar, India.
Ranjeet Kumar SinhaDepartment of Community Medicine, Patna Medical College, Patna 800004, Bihar, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endothelial keratoplasty (EK) is defined as an umbrella term comprising methods for selective surgical replacement of corneal endothelium and adjacent corneal tissue, which retains healthy portions of a patient's cornea while replacing diseased innermost corneal layer(s) with healthy donor tissue, to achieve corneal dehydration and transparency before the onset of irreversible stromal edema and permanent loss of corneal clarity. Recently, the pathophysiology of corneal decompensation is increasingly being researched upon. Consequent improvement in pharmacotherapy is progressively leading to reduction in the indications of EK. In addition, EK techniques have progressed towards using thinner tissue, optimizing visual outcomes. Improvements have enabled better donor tissue formulation, usage, and attachment, and surgical modifications have enhanced the tissue utilization in difficult clinical scenarios lowering failure and rejection. However, challenges are encountered in various complex clinical scenarios including eyes with prior intraocular surgery, complex anterior chamber anatomy, glaucoma, ocular surface disease

Indexed as

Cell-and tissue-based TherapyCorneal transplantationDescemet stripping endothelial keratoplastyImmunosuppression therapyRefractive surgical procedures

Identifiers

PMID40535500
PMCPMC11886285

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.