Evidence map›Paper›PMID 40535579›Full record

ArticleMindfulness2025

Sleep-Based Brain Age Is Reduced in Advanced Inner Engineering Meditators.

Jayme C Banks, Sepideh Hariri, Kestutis Kveraga, An Ouyang, Kaileigh Gallagher, Syed A Quadri, Ryan A Tesh, Preeti Upadhyay Reed, Robert J Thomas, M Brandon Westover and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Mindfulness, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jayme C BanksDepartment of Neurology, Massachusetts General Hospital (MGH), 55 Fruit Street, Boston, MA 02114 USA.
Sepideh HaririSadhguru Center for a Conscious Planet, Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Boston, MA USA.
Kestutis KveragaSadhguru Center for a Conscious Planet, Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Boston, MA USA.
An OuyangDepartment of Neurology, Massachusetts General Hospital (MGH), 55 Fruit Street, Boston, MA 02114 USA.
Kaileigh GallagherDepartment of Neurology, Massachusetts General Hospital (MGH), 55 Fruit Street, Boston, MA 02114 USA.
Syed A QuadriDepartment of Neurology, Massachusetts General Hospital (MGH), 55 Fruit Street, Boston, MA 02114 USA.
Ryan A TeshDepartment of Neurology, Massachusetts General Hospital (MGH), 55 Fruit Street, Boston, MA 02114 USA.
Preeti Upadhyay ReedSadhguru Center for a Conscious Planet, Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Boston, MA USA.
Robert J ThomasDivision of Pulmonary, Critical Care, & Sleep, Department of Medicine, Beth Israel Deaconess Medical Center (BIDMC), Boston, MA USA.
M Brandon WestoverDepartment of Neurology, Massachusetts General Hospital (MGH), 55 Fruit Street, Boston, MA 02114 USA.
Haoqi SunDepartment of Neurology, Massachusetts General Hospital (MGH), 55 Fruit Street, Boston, MA 02114 USA.
Balachundhar SubramaniamSadhguru Center for a Conscious Planet, Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Boston, MA USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: We aimed to quantify the effects of advanced meditation on brain electrical activity during sleep. This investigation addresses the need for objective neurophysiological measures of meditation's potential impact on brain aging and health. Method: This study was a single-site, prospective cohort study (conducted August 25, 2021, through September 26, 2021) of meditators attending the "Samyama Sadhana" retreat (September 1-5, 2021). Two healthy comparison groups and four comparison groups with varying degrees of age-related brain pathology are included. Using overnight electroencephalography, physiological measures of brain age were derived and subtracted from chronological age, measuring the deviation of apparent brain age from chronological age. Results: Thirty-four participants completed the study (average age = 38 years; 36% female). Estimated brain age index after adjustment by matching: meditators ( Conclusions: Long-term meditators exhibit lower brain age relative to matched control groups. This study suggests that advanced meditation enhances brain health. Preregistration: This study was not preregistered. Supplementary Information: The online version contains supplementary material available at 10.1007/s12671-025-02583-y.

Indexed as

Brain healthElectroencephalographyMeditationSleepWearable device

Identifiers

PMID40535579
PMCPMC12170783

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.