ReviewAmerican journal of translational research2025
Exploring the link between non-alcoholic fatty liver disease and depression: a systematic review and meta-analysis of bidirectional risk.
Review in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Mental Health Conditions and Incident Cancer: A Prospective Cohort Study of 402,255 UK Biobank Participants.International journal of cancer · 2026Article
- Associations between metabolic dysfunction-associated steatotic liver disease and physical and mental health-related quality of life in older adults.GeroScience · 2026Article
- Inverse Association Between Dietary Niacin Intake and Prevalence of Depressive Symptoms in Adults With Metabolic-Associated Fatty Liver Disease: A Cross-Sectional Study.Food science & nutrition · 2026Article
- Multi-Omics Evidence Linking Depression to MASLD Risk via Inflammatory Immune Signaling.Biomedicines · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study aims to consolidate evidence regarding the occurrence of depression among non-alcoholic fatty liver disease (NAFLD) patients and explore the bidirectional relationship between NAFLD and depression.
methodsThree major databases: Medline, Google Scholar, and ScienceDirect, were searched for relevant studies published up to August 2023 that report the incidence of depression in patients with NAFLD and investigate a correlation between NAFLD and depression. The quality of the studies was evaluated using the Joanna Briggs Institute checklist. The final pooled prevalence was reported with a 95% confidence interval (CI), and the pooled incidence of depression among NAFLD patients was summarized as a pooled Odds ratios (OR) with a 95% CI.
resultsA total of 16 studies were included in the analysis. The pooled prevalence of depression (15 studies) among NAFLD patients was 19% (95% CI: 16%-22%) (
conclusionRobust evidence supported a bidirectional link between NAFLD and depression. These findings underscore the importance of comprehensive patient care strategies that encompass both physical and mental well-being.
Indexed as
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.