Evidence map›Paper›PMID 40535666›Full record

ArticleAmerican journal of translational research2025

Local injection of platelet-rich plasma is effective for non-healing hand wounds.

Jiangqiang Chen, Zuhui Chen, Weibin Zheng, Xiangqian Shen

Abstract read
In one paragraph

Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jiangqiang ChenDepartment of Plastic Surgery, Tiantai County People's Hospital Tiantai County, Taizhou 317200, Zhejiang, China.
Zuhui ChenDepartment of Plastic Surgery, Tiantai County People's Hospital Tiantai County, Taizhou 317200, Zhejiang, China.
Weibin ZhengDepartment of Plastic Surgery, Tiantai County People's Hospital Tiantai County, Taizhou 317200, Zhejiang, China.
Xiangqian ShenDepartment of Plastic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine Hangzhou 310003, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the clinical efficacy of local platelet-rich plasma (PRP) injections in treating non-healing hand wounds.

methodsData of 80 patients with non-healing hand wounds were retrospectively selected for this study. Among them, 48 patients in the research group received local PRP injections, while 32 patients in the control group were treated with conventional dressing changes. The outcomes assessed included treatment efficacy, safety, frequency of dressing change, wound healing time, duration of hospitalization, treatment costs, wound healing rate, wound infection rate, Vancouver Scar Scale (VSS) scores, Bates-Jensen Wound Assessment Tool (BWAT) scores, Visual Analogue Scale (VAS) scores, serum wound growth factors, and patient satisfaction with wound appearance.

resultsThe research group demonstrated significantly superior outcomes compared to the control group, including higher overall treatment efficacy and wound healing rates. Furthermore, the research group exhibited a significantly lower incidence of adverse events, reduced frequency of dressing changes, shorter wound healing time, reduced hospitalization duration, lower treatment costs, and a lower infection rate. Post-treatment assessments revealed significantly lower VSS, BWAT, and VAS scores in the research group. Additionally, the upregulation of serum wound growth factors was more pronounced in the research group following treatment.

conclusionsLocal PRP injection demonstrates clear efficacy in the management of non-healing hand wounds.

Indexed as

clinical efficacylocal injectionnon-healing hand woundsPlatelet-rich plasma

Identifiers

PMID40535666
PMCPMC12170399

What Socratic holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.