Evidence map›Paper›PMID 40536096›Full record

ArticleeLife2025

Efficacy and mechanism of action of cipargamin as an antibabesial drug candidate.

Hang Li, Shengwei Ji, Nanang R Ariefta, Eloiza May S Galon, Shimaa A E S El-Sayed, Thom Do, Lijun Jia, Miako Sakaguchi, Masahito Asada, Yoshifumi Nishikawa and 3 more

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Hang Li *National Research Center for Protozoan Diseases, Obihiro University of Agriculture Veterinary Medicine, Obihiro, Japan.ORCID https://orcid.org/0009-0008-6361-8955
Shengwei Ji *National Research Center for Protozoan Diseases, Obihiro University of Agriculture Veterinary Medicine, Obihiro, Japan.ORCID https://orcid.org/0000-0001-7380-4809
Nanang R ArieftaNational Research Center for Protozoan Diseases, Obihiro University of Agriculture Veterinary Medicine, Obihiro, Japan.ORCID https://orcid.org/0000-0002-3012-6005
Eloiza May S GalonCollege of Veterinary Medicine and Biomedical Sciences, Cavite State University, Indang, Philippines.ORCID https://orcid.org/0000-0003-2411-8401
Shimaa A E S El-SayedNational Research Center for Protozoan Diseases, Obihiro University of Agriculture Veterinary Medicine, Obihiro, Japan.
Thom DoNational Research Center for Protozoan Diseases, Obihiro University of Agriculture Veterinary Medicine, Obihiro, Japan.
Lijun JiaDepartment of Veterinary Medicine, Agriculture College of Yanbian University, Yanji, China.
Miako SakaguchiCentral Laboratory, Institute of Tropical Medicine (NEKKEN), Nagasaki University, Nagasaki, Japan.
Masahito AsadaNational Research Center for Protozoan Diseases, Obihiro University of Agriculture Veterinary Medicine, Obihiro, Japan.ORCID https://orcid.org/0000-0003-0042-6856
Yoshifumi NishikawaNational Research Center for Protozoan Diseases, Obihiro University of Agriculture Veterinary Medicine, Obihiro, Japan.ORCID https://orcid.org/0000-0001-5005-6377
Xin QinSchool of Basic Medicine, Hubei University of Arts and Science, Xiangyang, China.ORCID https://orcid.org/0000-0001-6448-5180
Mingming LiuSchool of Basic Medicine, Hubei University of Arts and Science, Xiangyang, China.ORCID https://orcid.org/0000-0002-5935-6736
Xuenan XuanNational Research Center for Protozoan Diseases, Obihiro University of Agriculture Veterinary Medicine, Obihiro, Japan.ORCID https://orcid.org/0000-0003-2780-110X

Funding

Ministry of Agriculture, Forestry and Fisheries JPJ008837Ministry of Education, Culture, Sports, Science and Technology 22H0250906
6 · The paper itself

Abstract

Babesiosis is a disease brought on by intraerythrocytic parasites of the genus

Indexed as

Antiprotozoal AgentsBabesiaAnimalsBabesiosisDrug ResistanceInhibitory Concentration 50MiceAntiprotozoal AgentsBabesia spp.cipargamindrug resistanceinfectious diseasemicrobiologymouse

Identifiers

PMID40536096
PMCPMC12178600

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.