The Correlation between Hidradenitis Suppurativa and Irritable Bowel Diseases: A Systematic Review.

Zachrieh Alhaj, Zaid Almubaid, Gengi Kleto, Nabeel Ahmad, Vivian Rojas, Juan Pinto-Cuberos, Ayezel Munoz Gonzalez

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In one paragraph

Review in The Journal of clinical and aesthetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Zachrieh AlhajMessrs. Alhaj and Almubaid are with the John Sealy School of Medicine at the University of Texas Medical Branch in Galveston, Texas and the Department of Internal Medicine at the University of Texas Medical Branch in Galveston, Texas.

Zaid AlmubaidMessrs. Alhaj and Almubaid are with the John Sealy School of Medicine at the University of Texas Medical Branch in Galveston, Texas and the Department of Internal Medicine at the University of Texas Medical Branch in Galveston, Texas.

Gengi KletoMs. Kleto is with the John Sealy School of Medicine at the University of Texas Medical Branch in Galveston, Texas and the Department of Dermatology at the University of Texas Medical Branch in Galveston, Texas.

Nabeel AhmadMr. Ahmad is with the Tilamn J. Fertitta Family College of Medicine at the University of Houston in Houston, Texas.

Vivian RojasDrs. Pinto-Cuberos, Munoz Gonzalez, and Rojas are with the Department of Dermatology at the University of Texas Medical Branch in Galveston, Texas.

Juan Pinto-CuberosDrs. Pinto-Cuberos, Munoz Gonzalez, and Rojas are with the Department of Dermatology at the University of Texas Medical Branch in Galveston, Texas.

Ayezel Munoz GonzalezDrs. Pinto-Cuberos, Munoz Gonzalez, and Rojas are with the Department of Dermatology at the University of Texas Medical Branch in Galveston, Texas.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHidradenitis suppurativa (HS) is an inflammatory skin condition that presents with nodules or abscesses associated with sinus tracts. Inflammatory bowel diseases (IBD) are inflammatory gastrointestinal (GI) conditions presenting with irregular bowel movements. Although HS and IBDs may have similarities in their clinical presentation and pathophysiology, they can differ in their cutaneous manifestations. Both conditions are potentially caused by genetic changes in the human leukocyte antigen (HLA), cause skin inflammation, and are characterized by abscesses in the GI and sinus tracts.

objectiveWe sought to determine the extent of coincident IBD and HS and the associated risk factors.

methodsThe Ovid Medline database was searched for all current literature on the correlations between HS and IBD. Articles were then included and removed according to specific inclusion and exclusion criteria, and a systematic review was performed on the remaining articles.

resultsThirteen papers that met the inclusion and the exclusion criteria were selected, and after data collection, a significant correlation was found between the development of HS and IBD. Most of the articles reviewed stated that the corresponding association was a causal link between the two diseases. Furthermore, there were various risk factors and comorbidities associated with HS and the development of IBD, including smoking, obesity, perianal disease, and genetic predispositions such as HLA-B27 mutations. DISCUSSION: Studies show that there is a potential correlation with HS and IBDs. Additional research should to determine the genetic correlations between HS and IBDs and the underlying pathophysiological mechanism.

Indexed as

autoimmunitydermatologygastroenterologyHidradenitis suppurativairritable bowel diseases

Identifiers

PMID40538531

PMCPMC12175838

What Socratic holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.