Evidence map›Paper›PMID 40538551›Full record

ArticleFood chemistry: X2025

A systematic approach to analyzing catechins and catechin derivatives in Ceylon black tea using liquid chromatography coupled with triple quadrupole mass spectrometry.

Shanbo Zhang, Xinyao Long, Yiwen Xing, Kim-Huey Ee, Rui Min Vivian Goh, Yunle Huang, Aileen Pua, Lionel Jublot, Shao Quan Liu, Bin Yu

Abstract read
In one paragraph

Article in Food chemistry: X, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shanbo ZhangDepartment of Food Science and Technology, National University of Singapore, S14 Level 5, Science Drive 2, 117542, Singapore.
Xinyao LongDepartment of Food Science and Technology, National University of Singapore, S14 Level 5, Science Drive 2, 117542, Singapore.
Yiwen XingDepartment of Food Science and Technology, National University of Singapore, S14 Level 5, Science Drive 2, 117542, Singapore.
Kim-Huey EeMane SEA PTE LTD, 3 Biopolis Drive, #07-17/18/19 Synapse, 138623, Singapore.
Rui Min Vivian GohMane SEA PTE LTD, 3 Biopolis Drive, #07-17/18/19 Synapse, 138623, Singapore.
Yunle HuangMane SEA PTE LTD, 3 Biopolis Drive, #07-17/18/19 Synapse, 138623, Singapore.
Aileen PuaMane SEA PTE LTD, 3 Biopolis Drive, #07-17/18/19 Synapse, 138623, Singapore.
Lionel JublotMane SEA PTE LTD, 3 Biopolis Drive, #07-17/18/19 Synapse, 138623, Singapore.
Shao Quan LiuDepartment of Food Science and Technology, National University of Singapore, S14 Level 5, Science Drive 2, 117542, Singapore.
Bin YuMane SEA PTE LTD, 3 Biopolis Drive, #07-17/18/19 Synapse, 138623, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The structural complexity and limited standards for catechin derivatives in black tea present significant analytical challenges in tea research. This study aimed to develop a systematic approach to extract and analyze catechins and derivatives in Ceylon black tea from four Sri Lankan regions (Dimbula, Nuwara Eliya, Uva, Ruhuna) using optimized extraction conditions, LC-QQQ/MS, and antioxidant assays. A design of experiment (DoE) optimized solvent (0-100 % acetone-water), temperature (30-60 °C), and time (0-150 min), identifying 49.8 % acetone, 123.6 min with sonication, and 49.8 °C as optimal (desirability 0.743). Twelve catechin-related compounds were identified by LC-QQQ/MS, including theaflavins and tentatively annotated derivatives. TPC, TFC, DPPH, and ABTS assays showed Nuwara Eliya tea had the highest antioxidant capacity, linked to elevated polyphenols and flavonoids. This workflow offers a robust framework for studying catechin derivatives with limited standards, offering a practical solution for black tea research and quality assessment.

Indexed as

Catechin derivativesCeylon black teaDesign of experimentLC-QQQ/MS

Identifiers

PMID40538551
PMCPMC12177154

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.