Evidence map›Paper›PMID 40539000›Full record

ArticleGlomerular diseases

Cardiovascular Events in Lupus Nephritis: A Systematic Review and Meta-Analysis.

Mehrbod Vakhshoori, Giv Heidari-Bateni, Roy O Mathew, Amir Abdipour, Noha S Daher, Swapnil Hiremath, Mohamed Hassanein, Mohadese Golsorkhi, Niloufar Ebrahimi, Arvind Kumar Singh and 1 more

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In one paragraph

Article in Glomerular diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Myocardial infarction in rheumatic diseases.Rheumatology international · 2025
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mehrbod VakhshooriDivision of Nephrology, Department of Medicine, Loma Linda University Medical Center, Loma Linda, CA, USA.
Giv Heidari-BateniDivision of Cardiology, Arrowhead Regional Medical Center, California University of Science and Medicine, Colton, CA, USA.
Roy O MathewDepartment of Medicine, Loma Linda VA Health Care System, Loma Linda, CA, USA.
Amir AbdipourDivision of Nephrology, Department of Medicine, Loma Linda University Medical Center, Loma Linda, CA, USA.
Noha S DaherAllied Health Studies, School of Allied Health Professions, Loma Linda University Health, Loma Linda, CA, USA.
Swapnil HiremathDivision of Nephrology, Department of Medicine, University of Ottawa, Ottawa, ON, Canada.
Mohamed HassaneinDepartment of Nephrology and Hypertension, Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA.
Mohadese GolsorkhiPsychiatry Department, Brookdale Medical Center, New York, NY, USA.
Niloufar EbrahimiDivision of Nephrology, Department of Medicine, Loma Linda University Medical Center, Loma Linda, CA, USA.
Arvind Kumar SinghConsultant Nephrologist, NHS Foundation Trust, Gloucestershire Royal Hospital, Gloucester, UK.
Sayna NorouziDivision of Nephrology, Department of Medicine, Loma Linda University Medical Center, Loma Linda, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Systemic lupus erythematous (SLE) is known to be associated with cardiovascular events (CVEs). However, the incidence of CVE has not been thoroughly investigated in lupus nephritis (LN) patients. In this meta-analysis, we aimed to assess the incidence of CVE in patients with LN. Methods: We performed a literature search in PubMed, Scopus, and Web of Science database for studies reporting CVE (myocardial infarction [MI], heart failure, cerebrovascular accident [CVA] [i.e., ischemic or hemorrhagic stroke or transient ischemic attack], any cardiovascular- or cerebrovascular-related disease or death) in patients with LN. In addition, subgroup analyses were conducted according to geographical locations and kidney disease status. We also separately reported the incidence rate of MI, CVA, and cardiovascular- or cerebrovascular-related deaths, with CVE and MI risk in patients with LN. Results: Twenty-one records, encompassing 29,489 subjects, were included. The overall CVE incidence was 9% (95% confidence interval [CI]: 6-12%). Specifically, the incidence of MI (8 studies, Conclusion: CVE occurrence among individuals with LN is significant, and this disease entity increases CVE risk, highlighting the importance of implementing early therapeutic interventions to prevent poor outcomes.

Indexed as

Cardiovascular diseaseIncidenceLupus nephritisMortalityPrevalence

Identifiers

PMID40539000
PMCPMC12178181

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.