Evidence mapPaperPMID 40539013Full record

ReviewPediatric investigation2025

Anemia and retinopathy of prematurity: A narrative review.

Minali Prasad, David Dombrovsky, Stephen P Christiansen, Ellen C Ingolfsland

Abstract readReview
In one paragraph

Review in Pediatric investigation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Minali PrasadBoston University Chobanian & Avedisian School of Medicine Boston Massachusetts USA.
David DombrovskyDepartment of Biology Union College Schenectady New York USA.
Stephen P ChristiansenDepartment of Ophthalmology Boston Medical Center Boston University Chobanian & Avedisian School of Medicine Boston Massachusetts USA.ORCID https://orcid.org/0000-0001-5489-5354
Ellen C IngolfslandDepartment of Pediatrics Division of Neonatology University of Minnesota Minneapolis Minnesota USA.

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UM1TR004405 · UNIVERSITY OF MINNESOTA · 2025 to 2025
$7.7M
CTSA K12 Program at University of MinnesotaK12TR004373 · NCATS · UNIVERSITY OF MINNESOTA · 2024 to 2025
$2.1M
NCATS NIH HHS K12 TR004373NCATS NIH HHS UM1 TR004405
6 · The paper itself

Abstract

Retinopathy of prematurity (ROP) and anemia are often comorbid in preterm and low birth weight infants in the United States. However, the relationship between ROP and anemia in infants is unclear across prospective and retrospective studies due to confounding from other comorbidities of prematurity and variable study designs. Molecular mechanisms that may underlie this association include tissue hypoxia, oxidative stress, inflammation, and the timing of onset of anemia relative to the phase of ROP. Furthermore, maternal or neonatal disruptions in iron homeostasis, leading to either iron deficiency or accumulation, have been associated with ROP. Further studies, including randomized clinical trials, are needed to better elucidate the association between ROP and anemia, as well as the impact of the timing of the onset of anemia.

Indexed as

AnemiaIron homeostasisRetinopathy of prematurity

Identifiers

PMID40539013
PMCPMC12175631

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.