Evidence map›Paper›PMID 40540322›Full record

ArticleJournal of natural products2025

Modulation of Estrogen Receptor Activity by the Phytoalexin Tuberosin Produced from Elicited Kudzu (

Jorge A Belgodere, Jack R Elliott, Megan C Benz, G Wills Kpeli, Steven Elliott, Isaac J Ponder, Geoffroy E R Sanga Pema, Peng Ma, Sophie R Dietrich, Thomas Cheng and 16 more

Abstract read
In one paragraph

Article in Journal of natural products, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Jorge A BelgodereTulane Department of Medicine, Section of Hematology & Medical Oncology, Tulane University Health Science Center, New Orleans, Louisiana 70112, United States.ORCID 0000-0003-3399-4796
Jack R ElliottTulane Department of Medicine, Section of Hematology & Medical Oncology, Tulane University Health Science Center, New Orleans, Louisiana 70112, United States.
Megan C BenzTulane Department of Medicine, Section of Hematology & Medical Oncology, Tulane University Health Science Center, New Orleans, Louisiana 70112, United States.
G Wills KpeliDepartment of Biomedical Engineering, Tulane University, New Orleans, Louisiana 70112, United States.
Steven ElliottTulane Department of Medicine, Section of Hematology & Medical Oncology, Tulane University Health Science Center, New Orleans, Louisiana 70112, United States.ORCID 0000-0003-1167-867X
Isaac J PonderDepartment of Biological and Agricultural Engineering, Louisiana State University and Agricultural Center, Baton Rouge, Louisiana 70803, United States.
Geoffroy E R Sanga PemaTulane Department of Medicine, Section of Hematology & Medical Oncology, Tulane University Health Science Center, New Orleans, Louisiana 70112, United States.
Peng MaXavier University School of Pharmacy, Xavier University, New Orleans, Louisiana 70125, United States.
Sophie R DietrichTulane Department of Medicine, Section of Hematology & Medical Oncology, Tulane University Health Science Center, New Orleans, Louisiana 70112, United States.
Thomas ChengTulane Department of Medicine, Section of Hematology & Medical Oncology, Tulane University Health Science Center, New Orleans, Louisiana 70112, United States.
Khoa NguyenTulane Department of Medicine, Section of Hematology & Medical Oncology, Tulane University Health Science Center, New Orleans, Louisiana 70112, United States.
Syreeta L TilghmanPharmaceutical Sciences Division, College of Pharmacy and Pharmaceutical Sciences, Florida A&M University, Tallahassee, Florida 32307, United States.
Binghao ZouDepartment of Structural and Cellular Biology, Tulane University School of Medicine, New Orleans, Louisiana 70112, United States.
Muralidharan AnbalaganTulane Cancer Center, Tulane University, New Orleans, Louisiana 70112, United States.
Brian G RowanTulane Cancer Center, Tulane University, New Orleans, Louisiana 70112, United States.
Robert H NewmanDepartment of Biology, North Carolina A&T State University, Greensboro, North Carolina 27411, United States.ORCID 0000-0002-3865-0266
Mark MondrinosTulane Cancer Center, Tulane University, New Orleans, Louisiana 70112, United States.ORCID 0000-0002-2704-9440
Jayalakshmi SridharDepartment of Chemistry, Xavier University of Louisiana, New Orleans, Louisiana 70125, United States.ORCID 0000-0002-4424-9874
Thomas E WieseXavier University School of Pharmacy, Xavier University, New Orleans, Louisiana 70125, United States.
Simak AliDepartment of Surgery and Cancer, Imperial College London Hammersmith Hospital Campus, W12 0NN London, U.K.
Van T HoangTulane Department of Medicine, Section of Hematology & Medical Oncology, Tulane University Health Science Center, New Orleans, Louisiana 70112, United States.ORCID 0000-0002-1561-0915
Bridgette M Collins-BurowTulane Department of Medicine, Section of Hematology & Medical Oncology, Tulane University Health Science Center, New Orleans, Louisiana 70112, United States.
Elizabeth C MartinTulane Department of Medicine, Section of Hematology & Medical Oncology, Tulane University Health Science Center, New Orleans, Louisiana 70112, United States.
Hamed K AbbasU.S. Department of Agriculture, Agricultural Research Service, Southeast Area, Stoneville, Mississippi 38776, United States.
Stephen M BouéU.S. Department of Agriculture, Agricultural Research Service, Southern Regional Research Center, New Orleans, Louisiana 70179, United States.ORCID 0000-0002-2790-4427
Matthew E BurowTulane Department of Medicine, Section of Hematology & Medical Oncology, Tulane University Health Science Center, New Orleans, Louisiana 70112, United States.ORCID 0000-0002-0642-6630

Funding

CTSA K12 Program at the University of Alabama at BirminghamK12TR004769 · NCATS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Renee A. Heffron, Lucio Miele · 2024 to 2026
$4.8M
Identification and characterization of chemical probes for interrogation of the NEK family of kinases in cancer (Diversity Supplement - Belgodere)R01CA273095 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUROW, MATTHEW E., DREWRY, DAVID HAROLD · 2022 to 2025
$2.9M
Redox regulation of protein kinase function: biochemical mechanisms and cellular consequencesR35GM153737 · NIGMS · NORTH CAROLINA AGRI & TECH ST UNIV · PI Robert Howard Newman · 2024 to 2026
$1.1M
NCATS NIH HHS K12 TR004769NCI NIH HHS R01 CA273095NIGMS NIH HHS R35 GM153737
6 · The paper itself

Abstract

Kudzu's invasive nature has contributed to its classification as a weed, as it frequently outcompetes native plant species, leading to extensive overgrowth. Efforts to control kudzu have proven challenging, with moderate success using physical or biological agents. In this study, we evaluated the effects of two such control agents, ultraviolet C radiation and

Indexed as

IsoflavonesPuerariaReceptors, EstrogenSesquiterpenesCell ProliferationEstrogen Receptor alphaHEK293 CellsHumansMCF-7 CellsMolecular StructurePhytoalexinsEstrogen Receptor alphaIsoflavonesPhytoalexinsReceptors, EstrogenSesquiterpenestuberosin

Identifiers

PMID40540322
PMCPMC12305667

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.